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Disc Medicine
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Overview Fund Activity

152 hedge funds and large institutions have $1.68B invested in Disc Medicine in 2024 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 50 increasing their positions, 44 reducing their positions, and 15 closing their positions.

Holders
152
Holders Change
+20
Holders Change %
+15.15%
% of All Funds
2.02%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.11%
New
37
Increased
50
Reduced
44
Closed
15
Calls
$3.7M
Puts
$2.24M
Net Calls
+$1.46M
Net Calls Change
+$1.91M

Top Buyers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$118M
2
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$77.2M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$88.4M
4
AC
4
Armistice Capital
New York
$22.6M
5
Citadel Advisors
5
Citadel Advisors
Florida
$37.5M

Top Sellers

1
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$62.4M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$852K
3
LGM
3
Logos Global Management
California
$12.7M
4
Wellington Management Group
4
Wellington Management Group
Massachusetts
$88.5M
5
DM
5
Deerfield Management
New York
$38.1M
Name Market Value Shares Shares
Change 		Shares
Change %
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$159M 2,509,456 – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$118M 1,866,248 +1,459,434 +359%
BlackRock
3
BlackRock
New York
$118M 1,859,732 +8,579 +0.5%
O
4
OrbiMed
New York
$113M 1,785,571 – –
FLSM
5
Frazier Life Sciences Management
California
$111M 1,754,834 – –
PBA
6
Paradigm Biocapital Advisors
New York
$95M 1,497,720 – –
Wellington Management Group
7
Wellington Management Group
Massachusetts
$88.5M 1,395,405 -444,821 -24%
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$88.4M 1,394,637 +262,690 +23%
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$77.2M 1,217,815 +467,988 +62%
Vanguard Group
10
Vanguard Group
Pennsylvania
$67.7M 1,068,246 +18,716 +2%
BCLSI
11
Bain Capital Life Sciences Investors
Massachusetts
$62.4M 983,500 -812,235 -45%
State Street
12
State Street
Massachusetts
$48.7M 768,735 -59,175 -7%
DM
13
Deerfield Management
New York
$38.1M 600,515 -422,750 -41%
Citadel Advisors
14
Citadel Advisors
Florida
$37.5M 591,271 +180,247 +44%
SVCM
15
Saturn V Capital Management
Texas
$32.3M 509,406 -1,635 -0.3%
TCM
16
TCG Crossover Management
California
$30.9M 486,957 – –
Geode Capital Management
17
Geode Capital Management
Massachusetts
$30M 472,706 -2,013 -0.4%
WP
18
Woodline Partners
California
$25.1M 396,600 +19,538 +5%
AC
19
Armistice Capital
New York
$22.6M 356,000 +196,000 +123%
Adage Capital Partners
20
Adage Capital Partners
Massachusetts
$22.2M 350,000 -200,000 -36%
MB
21
MPM BioImpact
Massachusetts
$22M 346,401 +34,640 +11%
FCMV
22
Foresite Capital Management V
California
$19M 299,069 – –
Victory Capital Management
23
Victory Capital Management
Texas
$15M 236,244 +16,230 +7%
LGM
24
Logos Global Management
California
$12.7M 200,000 -735,000 -79%
Northern Trust
25
Northern Trust
Illinois
$11.9M 187,017 +16,299 +10%
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