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Disc Medicine

112 hedge funds and large institutions have $1.17B invested in Disc Medicine in 2023 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 41 increasing their positions, 28 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

220% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 10

46% more repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 28

30% more call options, than puts

Call options by funds: $12.4M | Put options by funds: $9.58M

26% more capital invested

Capital invested by funds: $934M → $1.17B (+$239M)

23% more funds holding

Funds holding: 91112 (+21)

2.76% less ownership

Funds ownership: 86.89%84.13% (-2.8%)

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
112
Holders Change
+21
Holders Change %
+23.08%
% of All Funds
1.63%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
32
Increased
41
Reduced
28
Closed
10
Calls
$12.4M
Puts
$9.58M
Net Calls
+$2.87M
Net Calls Change
+$8.4M
Name Holding Trade Value Shares
Change
Change in
Stake
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$148M -$9.74M -190,163 -7%
PBA
2
Paradigm Biocapital Advisors
New York
$138M +$57M +1,113,578 +88%
O
3
OrbiMed
New York
$98.3M -$29.1M -567,400 -25%
BCLSI
4
Bain Capital Life Sciences Investors
Massachusetts
$77M
PA
5
Perceptive Advisors
New York
$59.1M +$6.52M +127,404 +14%
BlackRock
6
BlackRock
New York
$50.2M +$11.5M +224,109 +35%
FLSM
7
Frazier Life Sciences Management
California
$45.3M +$6.66M +130,000 +20%
Vanguard Group
8
Vanguard Group
Pennsylvania
$44.2M +$5.07M +99,092 +15%
Adage Capital Partners
9
Adage Capital Partners
Massachusetts
$43.3M -$28.6M -558,405 -43%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$34.1M +$3.23M +63,092 +12%
State Street
11
State Street
Massachusetts
$32.3M -$5.54M -108,106 -16%
PCH
12
Polar Capital Holdings
United Kingdom
$31.6M
DM
13
Deerfield Management
New York
$26.8M +$1.76M +34,292 +8%
Janus Henderson Group
14
Janus Henderson Group
United Kingdom
$25.6M -$2.93M -57,202 -11%
RSCM
15
Rock Springs Capital Management
Maryland
$21M
AllianceBernstein
16
AllianceBernstein
Tennessee
$21M +$18.1M +353,955 +3,877%
5VM
17
5AM Venture Management
California
$17M -$7.38M -144,221 -33%
FCMV
18
Foresite Capital Management V
California
$14.1M
Geode Capital Management
19
Geode Capital Management
Massachusetts
$13.3M +$769K +15,021 +7%
Morgan Stanley
20
Morgan Stanley
New York
$13M +$8.97M +175,217 +354%
Franklin Resources
21
Franklin Resources
California
$12.8M +$3.09M +60,403 +38%
Fidelity Investments
22
Fidelity Investments
Massachusetts
$12.6M -$4.51M -88,021 -29%
Pictet Asset Management
23
Pictet Asset Management
Switzerland
$11.3M +$9.99M +195,091 New
IC
24
Ikarian Capital
Texas
$11.3M +$2.67M +52,216 +37%
Citadel Advisors
25
Citadel Advisors
Florida
$10.9M -$6.27M -122,507 -39%

IRON Hedge Fund Activity: Q4 2023 in Review

112 of the 6,859 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q4 2023, worth a combined $1.17B — up 26% from $934M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new IRON positions and 10 closed out — a net gain of 22 holders — while 41 added to existing stakes and 28 trimmed.

The largest buyer was Paradigm Biocapital Advisors, adding an estimated $57M. The largest seller was Novo Holdings A/S, exiting entirely with an estimated $51.2M sold.

  • 112 institutional investors held Disc Medicine (IRON) as of Q4 2023, up from 91 in Q3 2023.
  • Funds reported $1.17B of Disc Medicine stock for Q4 2023, up 26% quarter-over-quarter.
  • 32 funds opened new Disc Medicine positions in Q4 2023 and 10 closed out, a net change of +22 holders.
  • The largest Disc Medicine buyer in Q4 2023 was Paradigm Biocapital Advisors, an estimated $57M added.
  • The largest Disc Medicine seller in Q4 2023 was Novo Holdings A/S, an estimated $51.2M sold.

Based on aggregated 13F filings for Q4 2023.