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Disc Medicine
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Overview Fund Activity

112 hedge funds and large institutions have $1.17B invested in Disc Medicine in 2023 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 41 increasing their positions, 28 reducing their positions, and 10 closing their positions.

Holders
112
Holders Change
+21
Holders Change %
+23.08%
% of All Funds
1.64%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
32
Increased
41
Reduced
28
Closed
10
Calls
$12.4M
Puts
$9.58M
Net Calls
+$2.87M
Net Calls Change
+$8.4M

Top Buyers

1
PBA
1
Paradigm Biocapital Advisors
New York
$138M
2
AllianceBernstein
2
AllianceBernstein
Tennessee
$21M
3
BlackRock
3
BlackRock
New York
$50.2M
4
Pictet Asset Management
4
Pictet Asset Management
Switzerland
$11.3M
5
Morgan Stanley
5
Morgan Stanley
New York
$13M

Top Sellers

1
NHAS
1
Novo Holdings A/S
Denmark
$0
2
O
2
OrbiMed
New York
$98.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$43.3M
4
AVLSA
4
Atlas Venture Life Science Advisors
Massachusetts
$148M
5
5VM
5
5AM Venture Management
California
$17M
Name Market Value Shares Shares
Change 		Shares
Change %
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$148M 2,555,172 -190,163 -7%
PBA
2
Paradigm Biocapital Advisors
New York
$138M 2,385,857 +1,113,578 +88%
O
3
OrbiMed
New York
$98.3M 1,702,237 -567,400 -25%
BCLSI
4
Bain Capital Life Sciences Investors
Massachusetts
$77M 1,332,545 – –
PA
5
Perceptive Advisors
New York
$59.1M 1,023,045 +127,404 +14%
BlackRock
6
BlackRock
New York
$50.2M 868,440 +224,109 +35%
FLSM
7
Frazier Life Sciences Management
California
$45.3M 785,000 +130,000 +20%
Vanguard Group
8
Vanguard Group
Pennsylvania
$44.2M 764,544 +99,092 +15%
Adage Capital Partners
9
Adage Capital Partners
Massachusetts
$43.3M 750,000 -558,405 -43%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$34.1M 590,831 +63,092 +12%
State Street
11
State Street
Massachusetts
$32.3M 559,195 -108,106 -16%
PCH
12
Polar Capital Holdings
United Kingdom
$31.6M 546,915 – –
DM
13
Deerfield Management
New York
$26.8M 464,292 +34,292 +8%
Janus Henderson Group
14
Janus Henderson Group
United Kingdom
$25.6M 443,178 -57,202 -11%
RSCM
15
Rock Springs Capital Management
Maryland
$21M 363,468 – –
AllianceBernstein
16
AllianceBernstein
Tennessee
$21M 363,085 +353,955 +3,877%
5VM
17
5AM Venture Management
California
$17M 294,221 -144,221 -33%
FCMV
18
Foresite Capital Management V
California
$14.1M 243,513 – –
Geode Capital Management
19
Geode Capital Management
Massachusetts
$13.3M 229,419 +15,021 +7%
Morgan Stanley
20
Morgan Stanley
New York
$13M 224,774 +175,217 +354%
Franklin Resources
21
Franklin Resources
California
$12.8M 221,424 +60,403 +38%
Fidelity Investments
22
Fidelity Investments
Massachusetts
$12.6M 217,412 -88,021 -29%
Pictet Asset Management
23
Pictet Asset Management
Switzerland
$11.3M 195,091 +195,091 New
IC
24
Ikarian Capital
Texas
$11.3M 194,982 +52,216 +37%
Citadel Advisors
25
Citadel Advisors
Florida
$10.9M 187,924 -122,507 -39%
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