D.E. Shaw & Co
SEPN

D.E. Shaw & Co’s Septerna Inc SEPN Stock Holding History

D.E. Shaw & Co’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.56M Buy
+46,483
New +$1.32M ﹤0.01% 3409

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

D.E. Shaw & Co's SEPN Position: Q2 2026 in Review

D.E. Shaw & Co opened a new position in Septerna Inc (SEPN) in Q2 2026: 46,483 shares worth $1.56M. The stake represents ﹤0.01% of the portfolio and ranks #3409 among its holdings.

154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • D.E. Shaw & Co held 46,483 shares of Septerna Inc worth $1.56M as of Q2 2026.
  • Septerna Inc was a new D.E. Shaw & Co position in Q2 2026.
  • Septerna Inc made up ﹤0.01% of D.E. Shaw & Co's portfolio in Q2 2026, its #3409 holding.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.