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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

611 hedge funds and large institutions have $9.72B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 268 reducing their positions, and 102 closing their positions.

Holders
611
Holders Change
-61
Holders Change %
-9.08%
% of All Funds
8.2%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
268
Closed
102
Calls
$1.14B
Puts
$1.97B
Net Calls
-$834M
Net Calls Change
+$252M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
3
Citigroup
New York
$1.06B
4
Wells Fargo
4
Wells Fargo
California
$243M
5
JFG
5
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
1
Demars Financial Group
Washington
$247K
2
UBS Group
2
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$631M
4
HIIFS
4
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
5
Squarepoint
New York
$39.2M
Name Market Value Shares Shares
Change 		Shares
Change %
PPA
576
Painted Porch Advisors
California
$6.8K 82 – –
FIM
577
FWL Investment Management
Texas
$5.97K 72 -23 -24%
OWP
578
ORG Wealth Partners
Texas
$5.82K 70 -1,108 -94%
TIM
579
Total Investment Management
Arizona
$5.08K 61 +61 New
CBT
580
Crews Bank & Trust
Florida
$4.98K 60 – –
GTAM
581
Global Trust Asset Management
Florida
$4.15K 50 – –
OCM
582
Orion Capital Management
California
$4.15K 50 – –
HWA
583
HHM Wealth Advisors
Tennessee
$4.15K 50 – –
MWM
584
MorganRosel Wealth Management
Colorado
$4.15K 50 – –
RPA
585
Redwood Park Advisors
California
$4.15K 50 +14 +39%
HNB
586
Hilltop National Bank
Wyoming
$4.15K 50 +50 New
SSG
587
Summit Securities Group
New York
$4.15K 50 +50 New
DF
588
Dunhill Financial
United Kingdom
$4.15K 50 +50 New
JFA
589
JNBA Financial Advisors
Minnesota
$3.4K 41 +41 New
CAM
590
Costello Asset Management
Pennsylvania
$3.07K 37 – –
AG
591
AmeriFlex Group
Nevada
$3.02K 36 – –
TFGT
592
TS Financial Group (TSFG)
Illinois
$3K 32 – –
RCM
593
Raleigh Capital Management
North Carolina
$2.74K 33 +33 New
C
594
Covestor
United Kingdom
$2K 21 +11 +110%
CTC
595
Central Trust Company
Missouri
$1.99K 24 +24 New
FRA
596
Front Row Advisors
California
$1.66K 20 – –
MAWAG
597
Mid-American Wealth Advisory Group
Missouri
$1.66K 20 +20 New
CPBTD
598
Central Pacific Bank - Trust Division
Hawaii
$1.33K 16 – –
IUHSA
599
Itau Unibanco Holding S.A.
Brazil
$1.28K 1,000 +1,000 New
GC
600
Garde Capital
Washington
$1.24K 15 – –
22 23
24
25 26