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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

700 hedge funds and large institutions have $6.42B invested in SPDR S&P Biotech ETF in 2022 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 218 increasing their positions, 223 reducing their positions, and 93 closing their positions.

Holders
700
Holders Change
-2
Holders Change %
-0.28%
% of All Funds
12.11%
Holding in Top 10
33
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+3.13%
% of All Funds
0.57%
New
100
Increased
218
Reduced
223
Closed
93
Calls
$1.99B
Puts
$1.9B
Net Calls
+$89M
Net Calls Change
+$62.3M

Top Buyers

1
JPMorgan Chase & Co
1
JPMorgan Chase & Co
New York
$201M
2
Two Sigma Advisers
2
Two Sigma Advisers
New York
$105M
3
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$79.2M
4
Brown Advisory
4
Brown Advisory
Maryland
$77M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$52.6M

Top Sellers

1
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$165M
2
Goldman Sachs
2
Goldman Sachs
New York
$398M
3
UBS Group
3
UBS Group
Switzerland
$212M
4
Toronto Dominion Bank
4
Toronto Dominion Bank
Ontario, Canada
$144M
5
CI
5
Clal Insurance
Israel
$125M
Name Market Value Shares Shares
Change 		Shares
Change %
Bank Julius Baer & Co
26
Bank Julius Baer & Co
Switzerland
$50.8M 640,110 -64,877 -9%
BlackRock
27
BlackRock
New York
$48.7M 613,948 +142,837 +30%
DCM
28
DAFNA Capital Management
California
$44.9M 566,000 -47,000 -8%
IL
29
Investure LLC
Virginia
$44.5M 561,600 – –
D.E. Shaw & Co
30
D.E. Shaw & Co
New York
$40.9M 515,000 +515,000 New
Bessemer Group
31
Bessemer Group
New Jersey
$38.9M 490,762 +490,142 +79,055%
MPM
32
MBB Public Markets
Illinois
$38.9M 490,422 -348,427 -42%
Citadel Advisors
33
Citadel Advisors
Florida
$37.9M 478,261 +364,210 +319%
JHU
34
Johns Hopkins University
Maryland
$37.9M 478,065 +268,065 +128%
MMEA
35
Main Management ETF Advisors
California
$37.7M 475,745 +3,860 +0.8%
Ameriprise
36
Ameriprise
Minnesota
$36.3M 458,093 +235,318 +106%
CS
37
Credit Suisse
Switzerland
$36.2M 455,901 +203,663 +81%
CM
38
Castleark Management
Illinois
$35.6M 448,640 -195,250 -30%
HighTower Advisors
39
HighTower Advisors
Illinois
$34.3M 431,716 -134,511 -24%
MM
40
Main Management
California
$29.2M 368,135 +5,884 +2%
HF
41
HRT Financial
New York
$29.1M 367,107 +367,107 New
Susquehanna International Group
42
Susquehanna International Group
Pennsylvania
$25M 315,211 +76,438 +32%
G
43
GenTrust
Florida
$23.8M 300,521 +10,465 +4%
RJA
44
Raymond James & Associates
Florida
$23M 289,857 +29,748 +11%
EVM
45
Eaton Vance Management
Massachusetts
$22.8M 287,557 +31,459 +12%
Stifel Financial
46
Stifel Financial
Missouri
$22.8M 287,310 +95,439 +50%
SSA
47
Schonfeld Strategic Advisors
New York
$21.9M 275,838 +232,450 +536%
AFA
48
American Financial Advisors
Georgia
$21.5M 270,686 -9,431 -3%
ICG
49
InterOcean Capital Group
Tennessee
$21.2M 266,997 +10,229 +4%
WT
50
Whittier Trust
California
$21M 264,625 +158,110 +148%
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