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Tyra Biosciences
TYRA

Overview Fund Activity

117 hedge funds and large institutions have $500M invested in Tyra Biosciences in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 42 increasing their positions, 31 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
+4
Holders Change %
+3.54%
% of All Funds
1.59%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
21
Increased
42
Reduced
31
Closed
16
Calls
$233K
Puts
$50K
Net Calls
+$183K
Net Calls Change
+$213K

Top Buyers

1
VPC
Vestal Point Capital
New York
+$17.6M
2
KCM
Kynam Capital Management
New Jersey
+$17.4M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$9.25M
4
CC
Commodore Capital
New York
+$8.84M
5
TCM
TCG Crossover Management
California
+$8.45M

Top Sellers

1
BCM
Boxer Capital Management
California
-$28.2M
2
Fidelity Investments
Fidelity Investments
Massachusetts
-$13M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$2.78M
4
NCM
Nantahala Capital Management
Connecticut
-$1.39M
5
ABG
Ally Bridge Group
New York
-$631K
Name Holding Trade Value Shares
Change 		Shares
Change %
Morgan Stanley
26
Morgan Stanley
New York
$1.68M +$990K +106,441 +144%
Charles Schwab
27
Charles Schwab
California
$1.53M -$60.4K -6,492 -4%
PAMP
28
Polar Asset Management Partners
Ontario, Canada
$1.31M +$280K +30,134 +27%
Walleye Capital
29
Walleye Capital
New York
$1.31M +$723K +77,762 +123%
Axa
30
Axa
France
$1.19M +$1.19M +128,189 New
ABG
31
Ally Bridge Group
New York
$997K -$631K -67,819 -39%
Wellington Management Group
32
Wellington Management Group
Massachusetts
$968K +$85.8K +9,228 +10%
WP
33
Woodline Partners
California
$931K +$931K +100,108 New
Citadel Advisors
34
Citadel Advisors
Florida
$895K +$378K +40,695 +73%
CSS
35
Cubist Systematic Strategies
Connecticut
$854K -$167K -17,904 -16%
JPMorgan Chase & Co
36
JPMorgan Chase & Co
New York
$795K -$52.3K -5,625 -6%
ICCON
37
Investment Counsel Company of Nevada
Nevada
$791K – – –
Bank of America
38
Bank of America
North Carolina
$777K +$161K +17,364 +26%
Goldman Sachs
39
Goldman Sachs
New York
$725K +$129K +13,896 +22%
OC
40
Oppenheimer & Co
New York
$696K -$5.9K -634 -0.8%
BNP Paribas Financial Markets
41
BNP Paribas Financial Markets
France
$641K +$601K +64,632 +1,497%
Two Sigma Investments
42
Two Sigma Investments
New York
$603K +$173K +18,549 +40%
State of Wisconsin Investment Board
43
State of Wisconsin Investment Board
Wisconsin
$546K -$58.8K -6,327 -10%
Victory Capital Management
44
Victory Capital Management
Texas
$522K -$4.56K -490 -0.9%
Raymond James Financial
45
Raymond James Financial
Florida
$505K -$4.08K -439 -0.8%
Renaissance Technologies
46
Renaissance Technologies
New York
$478K +$207K +22,300 +77%
Two Sigma Advisers
47
Two Sigma Advisers
New York
$466K +$352K +37,800 +307%
NL
48
Nuveen LLC
North Carolina
$465K +$465K +49,998 New
Point72 Asset Management
49
Point72 Asset Management
Connecticut
$461K +$342K +36,817 +288%
BHCM
50
Brevan Howard Capital Management
Jersey
$431K +$431K +46,371 New
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