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Tyra Biosciences
TYRA

Overview Fund Activity

120 hedge funds and large institutions have $541M invested in Tyra Biosciences in 2025 Q2 according to their latest regulatory filings, with 18 funds opening new positions, 60 increasing their positions, 21 reducing their positions, and 14 closing their positions.

Holders
120
Holders Change
+3
Holders Change %
+2.56%
% of All Funds
1.61%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
18
Increased
60
Reduced
21
Closed
14
Calls
$1K
Puts
–
Net Calls
+$1K
Net Calls Change
-$182K

Top Buyers

1
CC
1
Commodore Capital
New York
$29.7M
2
RCM
2
RA Capital Management
Massachusetts
$117M
3
SCM
3
Sio Capital Management
New York
$7.75M
4
Balyasny Asset Management
4
Balyasny Asset Management
Illinois
$5.58M
5
Bank of America
5
Bank of America
North Carolina
$3.57M

Top Sellers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$117K
2
O
2
OrbiMed
New York
$7.7M
3
CPX
3
Canaan Partners XI
California
$34.5M
4
Pictet Asset Management
4
Pictet Asset Management
Switzerland
$0
5
VPC
5
Vestal Point Capital
New York
$25.4M
Name Market Value Shares Shares
Change 		Shares
Change %
Point72 Asset Management
26
Point72 Asset Management
Connecticut
$2.15M 224,700 +175,100 +353%
Citadel Advisors
27
Citadel Advisors
Florida
$2.07M 216,136 +119,854 +124%
Northern Trust
28
Northern Trust
Illinois
$1.96M 205,308 -11,139 -5%
CP
29
Caligan Partners
New York
$1.82M 189,950 +164,950 +660%
Charles Schwab
30
Charles Schwab
California
$1.7M 178,104 +13,996 +9%
Renaissance Technologies
31
Renaissance Technologies
New York
$1.29M 135,100 +83,700 +163%
Axa
32
Axa
France
$1.23M 128,400 +211 +0.2%
CSS
33
Cubist Systematic Strategies
Connecticut
$1.17M 122,036 +30,192 +33%
Two Sigma Investments
34
Two Sigma Investments
New York
$1.01M 105,825 +41,007 +63%
Goldman Sachs
35
Goldman Sachs
New York
$1.01M 105,595 +27,589 +35%
Wellington Management Group
36
Wellington Management Group
Massachusetts
$986K 103,078 -1,009 -1%
JPMorgan Chase & Co
37
JPMorgan Chase & Co
New York
$985K 102,917 +17,427 +20%
WP
38
Woodline Partners
California
$958K 100,108 – –
BNP Paribas Financial Markets
39
BNP Paribas Financial Markets
France
$935K 97,736 +28,786 +42%
Two Sigma Advisers
40
Two Sigma Advisers
New York
$833K 87,000 +36,900 +74%
ICCON
41
Investment Counsel Company of Nevada
Nevada
$814K 85,020 – –
Ameriprise
42
Ameriprise
Minnesota
$771K 80,602 +80,602 New
NL
43
Nuveen LLC
North Carolina
$770K 80,441 +30,443 +61%
State of Wisconsin Investment Board
44
State of Wisconsin Investment Board
Wisconsin
$732K 76,449 +17,737 +30%
OC
45
Oppenheimer & Co
New York
$708K 74,033 -772 -1%
A
46
AlphaQuest
New York
$699K 73,073 +43,451 +147%
JF
47
Jump Financial
Illinois
$681K 71,119 +43,170 +154%
ECM
48
ExodusPoint Capital Management
New York
$645K 67,442 +37,207 +123%
Raymond James Financial
49
Raymond James Financial
Florida
$605K 63,187 +8,843 +16%
Barclays
50
Barclays
United Kingdom
$589K 61,555 +19,044 +45%
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