Millennium Management’s Tyra Biosciences TYRA Stock Holding History

Millennium Management’s Portfolio TYRA Stock Details TYRA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$8.49M	Buy	221,581 +107,193	+94%	+$3.47M	﹤0.01%	2335
2025 Q4	$3.01M	Sell	114,388 -29,628	-21%	-$544K	﹤0.01%	3554
2025 Q3	$2.01M	Sell	144,016 -263,448	-65%	-$3M	﹤0.01%	4057
2025 Q2	$3.9M	Buy	407,464 +3,299	+0.8%	+$31.3K	﹤0.01%	3242
2025 Q1	$3.76M	Buy	404,165 +89,024	+28%	+$1.15M	﹤0.01%	3145
2024 Q4	$4.38M	Buy	315,141 +304,637	+2,900%	+$5.53M	﹤0.01%	2935
2024 Q3	$247K	Buy	+10,504	New	+$221K	﹤0.01%	5315
2023 Q3	–	Sell	-21,591	Closed	-$368K	–	6584
2023 Q2	$368K	Buy	21,591 +8,116	+60%	+$118K	﹤0.01%	4759
2023 Q1	$217K	Buy	+13,475	New	+$160K	﹤0.01%	5127
2022 Q1	–	Sell	-109,523	Closed	-$1.54M	–	7505
2021 Q4	$1.54M	Buy	109,523 +16,022	+17%	+$318K	﹤0.01%	4007
2021 Q3	$1.65M	Buy	+93,501	New	+$1.79M	﹤0.01%	4140

Other funds holding TYRA

RCM

RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

APMC

Alta Partners Management Company Jackson, Wyoming $151M AUM 296.21% 1-Year Est. Return

FCM

Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

PBA

Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return

Millennium Management's TYRA Position: Q1 2026 in Review

Millennium Management increased its Tyra Biosciences (TYRA) stake by 94% in Q1 2026, buying an estimated $3.47M and bringing the position to 221,581 shares worth $8.49M. The position accounts for ﹤0.01% of the portfolio, ranked #2335.

Millennium Management first reported a position in TYRA in Q3 2021 and has held it in 11 quarters since. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

Millennium Management held 221,581 shares of Tyra Biosciences worth $8.49M as of Q1 2026.
Millennium Management bought 107,193 Tyra Biosciences shares in Q1 2026, an estimated $3.47M.
Tyra Biosciences made up ﹤0.01% of Millennium Management's portfolio in Q1 2026, its #2335 holding.
Millennium Management first reported a position in Tyra Biosciences in Q3 2021 and has held it in 11 quarters since.
164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Millennium Management's 13F filing for Q1 2026, filed 15 May 2026.