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Tyra Biosciences
TYRA

Overview Fund Activity

120 hedge funds and large institutions have $541M invested in Tyra Biosciences in 2025 Q2 according to their latest regulatory filings, with 18 funds opening new positions, 60 increasing their positions, 21 reducing their positions, and 14 closing their positions.

Holders
120
Holders Change
+3
Holders Change %
+2.56%
% of All Funds
1.61%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
18
Increased
60
Reduced
21
Closed
14
Calls
$1K
Puts
–
Net Calls
+$1K
Net Calls Change
-$182K

Top Buyers

1
CC
1
Commodore Capital
New York
$29.7M
2
RCM
2
RA Capital Management
Massachusetts
$117M
3
SCM
3
Sio Capital Management
New York
$7.75M
4
Balyasny Asset Management
4
Balyasny Asset Management
Illinois
$5.58M
5
Bank of America
5
Bank of America
North Carolina
$3.57M

Top Sellers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$117K
2
O
2
OrbiMed
New York
$7.7M
3
CPX
3
Canaan Partners XI
California
$34.5M
4
Pictet Asset Management
4
Pictet Asset Management
Switzerland
$0
5
VPC
5
Vestal Point Capital
New York
$25.4M
Name Market Value Shares Shares
Change 		Shares
Change %
Jane Street
51
Jane Street
New York
$557K 58,168 +23,355 +67%
Bank of New York Mellon
52
Bank of New York Mellon
New York
$517K 54,039 +12,956 +32%
SPS
53
Susquehanna Portfolio Strategies
Pennsylvania
$466K 48,644 +48,644 New
UBS Group
54
UBS Group
Switzerland
$443K 46,268 -18 -0%
TI
55
Trexquant Investment
Connecticut
$428K 44,681 +44,681 New
Victory Capital Management
56
Victory Capital Management
Texas
$423K 44,190 -11,960 -21%
PP
57
PDT Partners
New York
$414K 43,310 +43,310 New
Dimensional Fund Advisors
58
Dimensional Fund Advisors
Texas
$399K 41,681 +6,969 +20%
Verition Fund Management
59
Verition Fund Management
Connecticut
$392K 40,939 -1,235 -3%
RhumbLine Advisers
60
RhumbLine Advisers
Massachusetts
$389K 40,685 +12,604 +45%
BHCM
61
Brevan Howard Capital Management
Jersey
$350K 36,594 -9,777 -21%
AllianceBernstein
62
AllianceBernstein
Tennessee
$341K 35,640 +18,070 +103%
XT
63
XTX Topco
Cayman Islands
$331K 34,601 +34,601 New
DTL
64
Dynamic Technology Lab
Singapore
$326K 34,115 +34,115 New
Squarepoint
65
Squarepoint
New York
$301K 31,408 +31,408 New
American Century Companies
66
American Century Companies
Missouri
$276K 28,854 +5,423 +23%
AA
67
ALPS Advisors
Colorado
$275K 28,729 +28,729 New
AQR Capital Management
68
AQR Capital Management
Connecticut
$275K 28,712 +28,712 New
Tudor Investment Corp
69
Tudor Investment Corp
Connecticut
$251K 26,265 +14,172 +117%
HS
70
HighVista Strategies
Massachusetts
$239K 24,962 +1,021 +4%
CC
71
Corton Capital
Ontario, Canada
$233K 24,346 +24,346 New
AI
72
Auour Investments
Massachusetts
$201K 21,020 – –
IIM
73
INTECH Investment Management
Florida
$191K 19,919 +6,322 +46%
Ohio Public Employees Retirement System (OPERS)
74
Ohio Public Employees Retirement System (OPERS)
Ohio
$177K 18,512 +18,512 New
Royal Bank of Canada
75
Royal Bank of Canada
Ontario, Canada
$156K 16,213 +15,536 +2,295%
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