Manulife (Manufacturers Life Insurance)’s Tyra Biosciences TYRA Stock Holding History

Manulife (Manufacturers Life Insurance)’s Portfolio TYRA Stock Details TYRA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$1.54M	Buy	40,224 +31,867	+381%	+$1.03M	﹤0.01%	1605
2025 Q4	$220K	Buy	+8,357	New	+$153K	﹤0.01%	2487
2025 Q1	–	Sell	-13,368	Closed	-$186K	–	2987
2024 Q4	$186K	Sell	13,368 -816	-6%	-$14.8K	﹤0.01%	2652
2024 Q3	$333K	Buy	+14,184	New	+$298K	﹤0.01%	2429

Other funds holding TYRA

RCM

RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

APMC

Alta Partners Management Company Jackson, Wyoming $127M AUM 230.85% 1-Year Est. Return

FCM

Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

PBA

Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return

Manulife (Manufacturers Life Insurance)'s TYRA Position: Q1 2026 in Review

Manulife (Manufacturers Life Insurance) increased its Tyra Biosciences (TYRA) stake by 381% in Q1 2026, buying an estimated $1.03M and bringing the position to 40,224 shares worth $1.54M. The position accounts for ﹤0.01% of the portfolio, ranked #1605.

Manulife (Manufacturers Life Insurance) first reported a position in TYRA in Q3 2024 and has held it in 4 quarters since. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

Manulife (Manufacturers Life Insurance) held 40,224 shares of Tyra Biosciences worth $1.54M as of Q1 2026.
Manulife (Manufacturers Life Insurance) bought 31,867 Tyra Biosciences shares in Q1 2026, an estimated $1.03M.
Tyra Biosciences made up ﹤0.01% of Manulife (Manufacturers Life Insurance)'s portfolio in Q1 2026, its #1605 holding.
Manulife (Manufacturers Life Insurance) first reported a position in Tyra Biosciences in Q3 2024 and has held it in 4 quarters since.
164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Manulife (Manufacturers Life Insurance)'s 13F filing for Q1 2026, filed 15 May 2026.