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Prime Medicine
PRME

Overview Fund Activity

120 hedge funds and large institutions have $145M invested in Prime Medicine in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 37 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
120
Holders Change
-3
Holders Change %
-2.44%
% of All Funds
1.61%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
29
Increased
37
Reduced
34
Closed
32
Calls
$1.42M
Puts
$1.22M
Net Calls
+$203K
Net Calls Change
+$320K

Top Buyers

1
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
$16M
2
CC
Casdin Capital
New York
$3.87M
3
SSA
Schonfeld Strategic Advisors
New York
$2.02M
4
Citadel Advisors
Citadel Advisors
Florida
$1.29M
5
FAM
Fred Alger Management
New York
$946K

Top Sellers

1
Millennium Management
Millennium Management
New York
$366K
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$162K
3
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group
Japan
$3.94M
4
NAMA
Nikko Asset Management Americas
New York
$3.89M
5
BBA
Baker Bros. Advisors
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
VIA
126
Virtus Investment Advisers
Connecticut
– -$109K -54,535 Closed
Two Sigma Advisers
127
Two Sigma Advisers
New York
– -$107K -53,900 Closed
Jacobs Levy Equity Management
128
Jacobs Levy Equity Management
New Jersey
– -$101K -50,514 Closed
BIG
129
Brooklyn Investment Group
New York
– -$79.5K -39,967 Closed
Verition Fund Management
130
Verition Fund Management
Connecticut
– -$76.1K -38,255 Closed
Cerity Partners
131
Cerity Partners
New York
– -$62.5K -31,387 Closed
BHCM
132
Brevan Howard Capital Management
Jersey
– -$56.7K -28,478 Closed
CF
133
Corebridge Financial
Texas
– -$55.3K -27,785 Closed
QC
134
Quadrature Capital
United Kingdom
– -$49.6K -24,802 Closed
AF
135
Avanza Fonder
Sweden
– -$42.8K -23,918 Closed
Envestnet Asset Management
136
Envestnet Asset Management
Illinois
– -$46.8K -23,515 Closed
BEI
137
Benjamin Edwards Inc
Missouri
– -$42K -21,101 Closed
CWM
138
CIBC World Markets
New York
– -$25K -12,585 Closed
American Century Companies
139
American Century Companies
Missouri
– -$22.7K -11,426 Closed
Pathstone Holdings
140
Pathstone Holdings
New Jersey
– -$22.4K -11,250 Closed
California State Teachers Retirement System (CalSTRS)
141
California State Teachers Retirement System (CalSTRS)
California
– -$8.18K -4,110 Closed
QCG
142
Quadrant Capital Group
Ohio
– -$3.67K -1,842 Closed
FHA
143
First Horizon Advisors
Tennessee
– -$1.85K -932 Closed
RA
144
Rise Advisors
New York
– -$1.14K -575 Closed
HFS
145
Hughes Financial Services
Virginia
– -$857 -480 Closed
PWMG
146
Prestige Wealth Management Group
New Jersey
– -$864 -434 Closed
Comerica Bank
147
Comerica Bank
Texas
– -$628 -315 Closed
CCM
148
Coldstream Capital Management
Washington
– -$564 -283 Closed
PA
149
Parallel Advisors
California
– -$219 -110 Closed
CI
150
Cordant Inc
Oregon
– -$66 -33 Closed
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