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Prime Medicine

192 hedge funds and large institutions have $343M invested in Prime Medicine in 2026 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 73 increasing their positions, 50 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

56% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 25

46% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 50

27% more call options, than puts

Call options by funds: $3.62M | Put options by funds: $2.86M

5% more funds holding

Funds holding: 183192 (+9)

2% more capital invested

Capital invested by funds: $337M → $343M (+$5.94M)

0.84% more ownership

Funds ownership: 53.75%54.59% (+0.84%)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
192
Holders Change
+9
Holders Change %
+4.92%
% of All Funds
2.36%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
39
Increased
73
Reduced
50
Closed
25
Calls
$3.62M
Puts
$2.86M
Net Calls
+$760K
Net Calls Change
+$1.05M
Name Holding Trade Value Shares
Change
Change in
Stake
Commonwealth Equity Services
126
Commonwealth Equity Services
Massachusetts
$57.2K -$68.4K -17,962 -52%
GCM
127
Graham Capital Management
Connecticut
$55.7K -$376K -98,665 -86%
MF
128
Magnetar Financial
Illinois
$54.9K +$60.1K +15,784 New
LCS
129
Levin Capital Strategies
New York
$52.2K
MAM
130
Martingale Asset Management
Massachusetts
$51.7K +$152 +40 +0.3%
Prudential Financial
131
Prudential Financial
New Jersey
$51.3K +$56.2K +14,755 New
SA
132
Sanctuary Advisors
Indiana
$48.4K -$2.91K -765 -5%
BEI
133
Benjamin Edwards Inc
Missouri
$48.2K +$52.7K +13,852 New
SIAP
134
Sterling Investment Advisors (Pennsylvania)
Pennsylvania
$46.6K
JEST
135
JTC Employer Solutions Trustee
Jersey
$46K
PCIA
136
Prime Capital Investment Advisors
Kansas
$45K -$4.22K -1,110 -8%
Cambridge Investment Research Advisors
137
Cambridge Investment Research Advisors
Iowa
$43K +$47K +12,337 New
Mercer Global Advisors
138
Mercer Global Advisors
Colorado
$42.8K +$46.8K +12,305 New
Pictet Asset Management
139
Pictet Asset Management
Switzerland
$42.1K +$46.1K +12,107 New
Raymond James Financial
140
Raymond James Financial
Florida
$41.9K -$57.1K -15,000 -55%
SFA
141
Sequoia Financial Advisors
Ohio
$40.6K +$44.4K +11,673 New
Teacher Retirement System of Texas
142
Teacher Retirement System of Texas
Texas
$38.5K -$4.48K -1,177 -10%
Victory Capital Management
143
Victory Capital Management
Texas
$37.6K +$61 +16 +0.1%
Wealthfront Advisers
144
Wealthfront Advisers
California
$36.1K +$39.5K +10,379 New
PCM
145
Polymer Capital Management
New York
$35.9K -$97.7K -25,664 -71%
FFM
146
Forum Financial Management
Illinois
$34.8K
GEA
147
Glen Eagle Advisors
New Jersey
$34.8K
FDCDDQ
148
Federation des caisses Desjardins du Quebec
Quebec, Canada
$33.1K -$9.52K -2,500 -21%
Mirae Asset Global Investments
149
Mirae Asset Global Investments
South Korea
$32.8K +$2.45K +643 +7%
Nisa Investment Advisors
150
Nisa Investment Advisors
Missouri
$32.5K +$18.3K +4,800 +106%