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Prime Medicine

192 hedge funds and large institutions have $343M invested in Prime Medicine in 2026 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 73 increasing their positions, 50 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

56% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 25

46% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 50

27% more call options, than puts

Call options by funds: $3.62M | Put options by funds: $2.86M

5% more funds holding

Funds holding: 183192 (+9)

2% more capital invested

Capital invested by funds: $337M → $343M (+$5.94M)

0.84% more ownership

Funds ownership: 53.75%54.59% (+0.84%)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
192
Holders Change
+9
Holders Change %
+4.92%
% of All Funds
2.36%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
39
Increased
73
Reduced
50
Closed
25
Calls
$3.62M
Puts
$2.86M
Net Calls
+$760K
Net Calls Change
+$1.05M
Name Holding Trade Value Shares
Change
Change in
Stake
VNT
176
Vanguard National Trust
Pennsylvania
$1.16K +$1.27K +334 New
PNC Financial Services Group
177
PNC Financial Services Group
Pennsylvania
$1.11K
BWA
178
Basecamp Wealth Advisors
Washington
$999
PFBT
179
Parkside Financial Bank & Trust
Missouri
$992
AAP
180
Arax Advisory Partners
Colorado
$800 +$875 +230 New
TWD
181
True Wealth Design
Ohio
$529 +$141 +37 +32%
FFA
182
Farther Finance Advisors
California
$522 +$316 +83 +117%
SS
183
Sunbelt Securities
Texas
$278
HI
184
Harbour Investments
Wisconsin
$258 +$282 +74 New
KFAS
185
Keating Financial Advisory Services
Kansas
$205 +$225 +59 New
NFSG
186
Newbridge Financial Services Group
Florida
$157 +$171 +45 New
US Bancorp
187
US Bancorp
Minnesota
$115 +$126 +33 New
National Bank of Canada
188
National Bank of Canada
Quebec, Canada
$35 +$38 +10 New
SIC
189
SJS Investment Consulting
Ohio
$35 +$38 +10 New
TPWA
190
Twin Peaks Wealth Advisors
California
$10 +$11 +3 New
IA
191
IFP Advisors
Florida
$7 -$30 -8 -80%
Point72 Asset Management
192
Point72 Asset Management
Connecticut
-$1.91M -551,030 Closed
Two Sigma Advisers
193
Two Sigma Advisers
New York
-$1.33M -383,500 Closed
Verition Fund Management
194
Verition Fund Management
Connecticut
-$1.01M -290,983 Closed
DFCM
195
Dark Forest Capital Management
Puerto Rico
-$784K -225,859 Closed
JF
196
Jump Financial
Illinois
-$597K -171,931 Closed
VF
197
Virtu Financial
New York
-$329K -94,778 Closed
Qube Research & Technologies (QRT)
198
Qube Research & Technologies (QRT)
United Kingdom
-$329K -94,670 Closed
BHCM
199
Brevan Howard Capital Management
Jersey
-$195K -56,088 Closed
Millennium Management
200
Millennium Management
New York
-$178K -51,335 Closed