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Prime Medicine

192 hedge funds and large institutions have $343M invested in Prime Medicine in 2026 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 73 increasing their positions, 50 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

56% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 25

46% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 50

27% more call options, than puts

Call options by funds: $3.62M | Put options by funds: $2.86M

5% more funds holding

Funds holding: 183192 (+9)

2% more capital invested

Capital invested by funds: $337M → $343M (+$5.94M)

0.84% more ownership

Funds ownership: 53.75%54.59% (+0.84%)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
192
Holders Change
+9
Holders Change %
+4.92%
% of All Funds
2.36%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
39
Increased
73
Reduced
50
Closed
25
Calls
$3.62M
Puts
$2.86M
Net Calls
+$760K
Net Calls Change
+$1.05M
Name Holding Trade Value Shares
Change
Change in
Stake
Royal Bank of Canada
151
Royal Bank of Canada
Ontario, Canada
$32K +$16.6K +4,365 +89%
New York State Common Retirement Fund
152
New York State Common Retirement Fund
New York
$29.4K
AIP
153
Ameritas Investment Partners
Nebraska
$29.3K +$9.54K +2,506 +42%
NS
154
NBC Securities
Alabama
$17.4K
S
155
SignatureFD
Georgia
$17.4K
AF
156
Allworth Financial
California
$15.3K +$4.91K +1,290 +41%
Osaic Holdings
157
Osaic Holdings
Arizona
$14.3K -$16.5K -4,331 -51%
GFM
158
GF Fund Management
China
$14K +$1.86K +489 +14%
SCM
159
Sterling Capital Management
North Carolina
$12K -$8.65K -2,274 -40%
FCG
160
Financial Connections Group
California
$12K
MIM
161
MTM Investment Management
South Carolina
$10.8K
OCWP
162
Owl Creek Wealth Partners
Colorado
$9.1K +$9.95K +2,615 New
Corient Private Wealth
163
Corient Private Wealth
Florida
$8.64K -$138K -36,333 -47%
EWA
164
EverSource Wealth Advisors
Alabama
$6.96K +$906 +238 +14%
SA
165
Scarborough Advisors
Maryland
$4.38K +$4 +1 +0.1%
EP
166
Essential Partners
California
$3.51K +$3K +787 +356%
NA
167
NewEdge Advisors
Louisiana
$3.48K
Optiver Holding
168
Optiver Holding
Netherlands
$3.1K +$2.79K +732 +458%
GI
169
GAMMA Investing
California
$2.25K +$2.04K +536 +483%
FG
170
Fairman Group
Pennsylvania
$1.74K
FFO
171
Fortitude Family Office
Arizona
$1.52K +$533 +140 +47%
SS
172
SBI Securities
Japan
$1.36K +$335 +88 +29%
MCM
173
MAI Capital Management
Ohio
$1.34K +$426 +112 +41%
CIAM
174
Caitong International Asset Management
Hong Kong
$1.33K -$146K -38,313 -99%
RIL
175
Rothschild Investment LLC
Illinois
$1.33K +$141 +37 +11%