Prime Medicine
PRME
PRME
180 hedge funds and large institutions have $336M invested in Prime Medicine in 2025 Q4 according to their latest regulatory filings, with 42 funds opening new positions, 65 increasing their positions, 40 reducing their positions, and 27 closing their positions.
New
Increased
Maintained
Reduced
Closed
more repeat investments, than reductions
Existing positions increased: | Existing positions reduced:
more first-time investments, than exits
New positions opened: | Existing positions closed:
more funds holding
Funds holding: →
less call options, than puts
Call options by funds: $ | Put options by funds: $
14.93% less ownership
Funds ownership: 68.63% → 53.71% (-15%)
34% less capital invested
Capital invested by funds: $512M → $336M (-$175M)
50% less funds holding in top 10
Funds holding in top 10: 2 → 1 (-1)
Holders
180
Holding in Top 10
1
Calls
$3.21M
Puts
$3.5M
Top Buyers
| 1 | +$16.9M | |
| 2 | +$13.7M | |
| 3 | +$11.6M | |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$9.5M |
| 5 |
Vanguard Group
Malvern,
Pennsylvania
|
+$6.88M |
Top Sellers
| 1 | -$16.6M | |
| 2 | -$15.6M | |
| 3 | -$14.3M | |
| 4 |
EC
EcoR1 Capital
San Francisco,
California
|
-$8.55M |
| 5 |
Millennium Management
New York
|
-$6.08M |
