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Prime Medicine

192 hedge funds and large institutions have $343M invested in Prime Medicine in 2026 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 73 increasing their positions, 50 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

56% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 25

46% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 50

27% more call options, than puts

Call options by funds: $3.62M | Put options by funds: $2.86M

5% more funds holding

Funds holding: 183192 (+9)

2% more capital invested

Capital invested by funds: $337M → $343M (+$5.94M)

0.84% more ownership

Funds ownership: 53.75%54.59% (+0.84%)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
192
Holders Change
+9
Holders Change %
+4.92%
% of All Funds
2.36%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
39
Increased
73
Reduced
50
Closed
25
Calls
$3.62M
Puts
$2.86M
Net Calls
+$760K
Net Calls Change
+$1.05M
Name Holding Trade Value Shares
Change
Change in
Stake
State of New Jersey Common Pension Fund D
101
State of New Jersey Common Pension Fund D
New Jersey
$107K +$117K +30,845 New
PFSRSONJ
102
Police & Firemen's Retirement System of New Jersey
New Jersey
$107K +$36.5K +9,585 +45%
IIM
103
INTECH Investment Management
Florida
$106K -$17.1K -4,498 -13%
TCA
104
Transcend Capital Advisors
New Jersey
$105K +$13.6K +3,570 +13%
SEI Investments
105
SEI Investments
Pennsylvania
$102K +$111K +29,183 New
Envestnet Asset Management
106
Envestnet Asset Management
Illinois
$101K -$13.5K -3,536 -11%
Manulife (Manufacturers Life Insurance)
107
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$100K -$10.4K -2,730 -9%
Creative Planning
108
Creative Planning
Kansas
$98.3K +$39.4K +10,354 +58%
EFM
109
E Fund Management
China
$94.3K +$103K +27,099 New
BBPWM
110
Blue Bell Private Wealth Management
Pennsylvania
$94K +$103K +27,015 New
VIA
111
Vanguard Investments Australia
Australia
$90.9K +$99.4K +26,124 New
APG
112
Abacus Planning Group
South Carolina
$87.7K
TCWA
113
Turtle Creek Wealth Advisors
Texas
$87K +$95.2K +25,000 New
Nomura Holdings
114
Nomura Holdings
Japan
$86.4K +$129 +34 +0.1%
ASRS
115
Arizona State Retirement System
Arizona
$86.3K +$2.69K +706 +3%
Group One Trading
116
Group One Trading
Illinois
$86.2K -$299K -78,447 -76%
ProShare Advisors
117
ProShare Advisors
Maryland
$79.9K -$12.1K -3,190 -12%
VPIM
118
Vanguard Personalized Indexing Management
California
$76.4K -$6.46K -1,697 -7%
TRCT
119
Tower Research Capital (TRC)
New York
$75.9K +$80K +21,007 +2,603%
SWM
120
Shelton Wealth Management
Texas
$69.8K
KK
121
KLP Kapitalforvaltning
Norway
$64.4K
Zurich Cantonal Bank
122
Zurich Cantonal Bank
Switzerland
$63.4K +$35.8K +9,411 +107%
SRL
123
Scientech Research LLC
New Jersey
$62.4K -$17K -4,462 -20%
VOYA Investment Management
124
VOYA Investment Management
Georgia
$60.4K -$556 -146 -0.8%
TDC
125
Thompson Davis & Co
Virginia
$60K -$20.9K -5,500 -24%