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Prime Medicine
PRME

Overview Fund Activity

119 hedge funds and large institutions have $144M invested in Prime Medicine in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 36 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
119
Holders Change
-4
Holders Change %
-3.25%
% of All Funds
1.6%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
29
Increased
36
Reduced
34
Closed
32
Calls
$1.21M
Puts
$1.12M
Net Calls
+$96K
Net Calls Change
+$213K

Top Buyers

1
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$16M
2
CC
2
Casdin Capital
New York
$3.87M
3
SSA
3
Schonfeld Strategic Advisors
New York
$2.02M
4
Citadel Advisors
4
Citadel Advisors
Florida
$1.29M
5
FAM
5
Fred Alger Management
New York
$946K

Top Sellers

1
Millennium Management
1
Millennium Management
New York
$366K
2
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$162K
3
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$3.94M
4
NAMA
4
Nikko Asset Management Americas
New York
$3.89M
5
BBA
5
Baker Bros. Advisors
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
VOYA Investment Management
76
VOYA Investment Management
Georgia
$42.5K 17,222 – –
PFSRSONJ
77
Police & Firemen's Retirement System of New Jersey
New Jersey
$42.2K 17,092 – –
ProShare Advisors
78
ProShare Advisors
Maryland
$41.7K 16,871 -1,323 -7%
CGL
79
Clarius Group LLC
Washington
$39.7K 16,080 – –
PCIA
80
Prime Capital Investment Advisors
Kansas
$39.6K 16,031 -8,230 -34%
SC
81
Savant Capital
Illinois
$37.5K 15,166 +15,166 New
Commonwealth Equity Services
82
Commonwealth Equity Services
Massachusetts
$37K 14,942 +14,942 New
CIBC World Market
83
CIBC World Market
Ontario, Canada
$35.4K 14,326 -2,689 -16%
Invesco
84
Invesco
Georgia
$33.7K 13,662 -1,174 -8%
JEST
85
JTC Employer Solutions Trustee
Jersey
$33K 13,249 +13,249 New
VF
86
Virtu Financial
New York
$31K 12,545 +12,545 New
RS
87
R Squared
Hong Kong
$30.9K 12,519 +12,519 New
TRCT
88
Tower Research Capital (TRC)
New York
$30.2K 12,246 +2,337 +24%
State Board of Administration of Florida Retirement System
89
State Board of Administration of Florida Retirement System
Florida
$28.2K 11,420 – –
FIM
90
Freedom Investment Management
Connecticut
$25.8K 10,432 +10,432 New
Creative Planning
91
Creative Planning
Kansas
$25.1K 10,145 +10,145 New
FCM
92
Fogel Capital Management
Florida
$24.7K 10,000 +10,000 New
New York State Common Retirement Fund
93
New York State Common Retirement Fund
New York
$21K 8,434 – –
Royal Bank of Canada
94
Royal Bank of Canada
Ontario, Canada
$13K 5,145 +3,505 +214%
Mirae Asset Global Investments
95
Mirae Asset Global Investments
South Korea
$12.5K 5,072 +683 +16%
Legal & General Group
96
Legal & General Group
United Kingdom
$12.1K 4,899 -1,016 -17%
Nisa Investment Advisors
97
Nisa Investment Advisors
Missouri
$10.5K 4,236 +3,921 +1,245%
AIP
98
Ameritas Investment Partners
Nebraska
$9.64K 3,901 – –
GFM
99
GF Fund Management
China
$8.29K 3,358 – –
AB
100
Amalgamated Bank
New York
$5K 1,957 – –
2 3
4
5 6