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Prime Medicine
PRME

Overview Fund Activity

119 hedge funds and large institutions have $144M invested in Prime Medicine in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 36 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
119
Holders Change
-4
Holders Change %
-3.25%
% of All Funds
1.6%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
29
Increased
36
Reduced
34
Closed
32
Calls
$1.21M
Puts
$1.12M
Net Calls
+$96K
Net Calls Change
+$213K

Top Buyers

1
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$16M
2
CC
2
Casdin Capital
New York
$3.87M
3
SSA
3
Schonfeld Strategic Advisors
New York
$2.02M
4
Citadel Advisors
4
Citadel Advisors
Florida
$1.29M
5
FAM
5
Fred Alger Management
New York
$946K

Top Sellers

1
Millennium Management
1
Millennium Management
New York
$366K
2
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$162K
3
Sumitomo Mitsui Trust Group
3
Sumitomo Mitsui Trust Group
Japan
$3.94M
4
NAMA
4
Nikko Asset Management Americas
New York
$3.89M
5
BBA
5
Baker Bros. Advisors
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
T. Rowe Price Associates
51
T. Rowe Price Associates
Maryland
$162K 65,320 -1,501,872 -96%
HF
52
HRT Financial
New York
$158K 64,167 +64,167 New
PCM
53
Prelude Capital Management
New York
$102K 41,288 +41,288 New
MIM
54
MetLife Investment Management
New Jersey
$96.4K 39,014 +39,014 New
JIP
55
Jaffetilchin Investment Partners
Florida
$93.2K 37,744 +37,744 New
AC
56
AXQ Capital
New Jersey
$92.8K 37,587 +37,587 New
IC
57
IEQ Capital
California
$88.5K 35,830 +948 +3%
Squarepoint
58
Squarepoint
New York
$88.5K 35,826 +35,826 New
Carson Wealth (CWM LLC)
59
Carson Wealth (CWM LLC)
Nebraska
$88K 35,761 +15,295 +75%
Citigroup
60
Citigroup
New York
$85.9K 34,759 -7,543 -18%
IEFM
61
IQ EQ Fund Management
Ireland
$83.1K 33,660 -56,210 -63%
JPMorgan Chase & Co
62
JPMorgan Chase & Co
New York
$81.6K 33,035 -2,628 -7%
Wealth Enhancement Advisory Services
63
Wealth Enhancement Advisory Services
Minnesota
$80.9K 26,007 +13,777 +113%
CAG
64
Crestwood Advisors Group
Massachusetts
$78.3K 31,687 – –
IIM
65
INTECH Investment Management
Florida
$76.1K 30,810 -24,136 -44%
SG Americas Securities
66
SG Americas Securities
New York
$69K 27,919 -23,537 -46%
Jane Street
67
Jane Street
New York
$67K 27,145 +27,145 New
BNP Paribas Financial Markets
68
BNP Paribas Financial Markets
France
$66K 26,735 -4,587 -15%
CUAMC
69
China Universal Asset Management Company
China
$65.1K 26,370 +61 +0.2%
KWM
70
Kingsview Wealth Management
Oregon
$61.8K 25,000 +25,000 New
VPIM
71
Vanguard Personalized Indexing Management
California
$57.3K 23,191 +7,954 +52%
TD Asset Management
72
TD Asset Management
Ontario, Canada
$56.6K 22,910 -23,524 -51%
HighTower Advisors
73
HighTower Advisors
Illinois
$52.7K 21,354 -292 -1%
FDCDDQ
74
Federation des caisses Desjardins du Quebec
Quebec, Canada
$52.4K 21,200 +21,200 New
Manulife (Manufacturers Life Insurance)
75
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$51.8K 20,979 -3,945 -16%
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