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Prime Medicine

192 hedge funds and large institutions have $343M invested in Prime Medicine in 2026 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 73 increasing their positions, 50 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

56% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 25

46% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 50

27% more call options, than puts

Call options by funds: $3.62M | Put options by funds: $2.86M

5% more funds holding

Funds holding: 183192 (+9)

2% more capital invested

Capital invested by funds: $337M → $343M (+$5.94M)

0.84% more ownership

Funds ownership: 53.75%54.59% (+0.84%)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
192
Holders Change
+9
Holders Change %
+4.92%
% of All Funds
2.36%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
39
Increased
73
Reduced
50
Closed
25
Calls
$3.62M
Puts
$2.86M
Net Calls
+$760K
Net Calls Change
+$1.05M
Name Holding Trade Value Shares
Change
Change in
Stake
ECA
51
Elevate Capital Advisors
Colorado
$526K +$413K +108,403 +254%
Marshall Wace
52
Marshall Wace
United Kingdom
$494K +$540K +141,957 New
BCM
53
Bridgeway Capital Management
Texas
$469K
T. Rowe Price Associates
54
T. Rowe Price Associates
Maryland
$466K +$111K +29,202 +28%
AllianceBernstein
55
AllianceBernstein
Tennessee
$425K +$52.4K +13,770 +13%
Mirae Asset Global ETFs Holdings
56
Mirae Asset Global ETFs Holdings
Hong Kong
$421K +$28.2K +7,403 +6%
SPIA
57
Steward Partners Investment Advisory
New York
$409K -$3.62K -950 -0.8%
Fidelity International
58
Fidelity International
Bermuda
$401K -$1.51K -396 -0.3%
RhumbLine Advisers
59
RhumbLine Advisers
Massachusetts
$398K +$22.3K +5,860 +5%
EGM
60
Engineers Gate Manager
New York
$384K +$190K +49,858 +82%
PWM
61
Palumbo Wealth Management
New York
$356K +$63.6K +16,707 +20%
Invesco
62
Invesco
Georgia
$337K +$153K +40,096 +71%
PA
63
Profund Advisors
Maryland
$333K +$99.7K +26,201 +38%
TD Asset Management
64
TD Asset Management
Ontario, Canada
$328K
Squarepoint
65
Squarepoint
New York
$327K -$472K -123,976 -57%
Rockefeller Capital Management
66
Rockefeller Capital Management
New York
$318K -$114K -29,990 -25%
California State Teachers Retirement System (CalSTRS)
67
California State Teachers Retirement System (CalSTRS)
California
$301K -$1.74K -456 -0.5%
UBS AM
68
UBS AM
Illinois
$297K -$52.5K -13,800 -14%
Mariner
69
Mariner
Kansas
$273K +$160K +42,108 +116%
CIA
70
Concurrent Investment Advisors
Florida
$258K +$282K +74,177 New
IC
71
IEQ Capital
California
$258K +$140K +36,877 +99%
VIA
72
Virtus Investment Advisers
Connecticut
$231K +$6.17K +1,622 +2%
LPL Financial
73
LPL Financial
California
$231K +$128K +33,500 +102%
Legal & General Group
74
Legal & General Group
United Kingdom
$231K -$54.4K -14,305 -18%
Russell Investments Group
75
Russell Investments Group
United Kingdom
$224K +$219K +57,446 +841%