PRAX icon

Praxis Precision Medicines
PRAX

Overview Fund Activity

142 hedge funds and large institutions have $1.02B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 65 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
142
Holders Change
-7
Holders Change %
-4.7%
% of All Funds
1.9%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
65
Reduced
34
Closed
32
Calls
$26.3M
Puts
$15.5M
Net Calls
+$10.8M
Net Calls Change
+$15.8M

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
VR Adviser
New York
$0
2
Capital Research Global Investors
Capital Research Global Investors
California
$0
3
PA
Perceptive Advisors
New York
$31.7M
4
SCM
Soleus Capital Management
Connecticut
$40.7M
5
SCM
Silverarc Capital Management
Massachusetts
$421K
Name Holding Trade Value Shares
Change 		Shares
Change %
State of Wisconsin Investment Board
76
State of Wisconsin Investment Board
Wisconsin
$621K +$6.22K +148 +1%
AQR Capital Management
77
AQR Capital Management
Connecticut
$613K +$613K +14,580 New
JPMorgan Chase & Co
78
JPMorgan Chase & Co
New York
$586K +$103K +2,459 +21%
Jane Street
79
Jane Street
New York
$547K +$148K +3,514 +37%
Deutsche Bank
80
Deutsche Bank
Germany
$510K -$73K -1,737 -13%
GCP
81
GSA Capital Partners
United Kingdom
$505K -$40.8K -969 -7%
Citigroup
82
Citigroup
New York
$499K -$1.42M -33,766 -74%
Wells Fargo
83
Wells Fargo
California
$473K +$115K +2,735 +32%
AA
84
ALPS Advisors
Colorado
$462K -$166K -3,944 -26%
MIM
85
MetLife Investment Management
New Jersey
$442K -$3.24K -77 -0.7%
HSA
86
Hussman Strategic Advisors
Maryland
$442K – – –
Citadel Advisors
87
Citadel Advisors
Florida
$436K -$2.18M -51,844 -83%
SCM
88
Silverarc Capital Management
Massachusetts
$421K -$6.56M -156,074 -94%
IIM
89
INTECH Investment Management
Florida
$367K -$3.32K -79 -0.9%
BHCM
90
Brevan Howard Capital Management
Jersey
$358K +$358K +8,503 New
New York State Common Retirement Fund
91
New York State Common Retirement Fund
New York
$278K – – –
Two Sigma Investments
92
Two Sigma Investments
New York
$274K -$517K -12,299 -65%
Creative Planning
93
Creative Planning
Kansas
$273K +$273K +6,495 New
State Board of Administration of Florida Retirement System
94
State Board of Administration of Florida Retirement System
Florida
$270K +$16.2K +385 +6%
SPS
95
Susquehanna Portfolio Strategies
Pennsylvania
$242K +$242K +5,750 New
Cerity Partners
96
Cerity Partners
New York
$236K +$236K +5,611 New
PA
97
Profund Advisors
Maryland
$221K -$35.6K -847 -14%
VF
98
Virtu Financial
New York
$213K +$213K +5,058 New
JFG
99
Jefferies Financial Group
New York
$210K +$210K +5,000 New
Norges Bank
100
Norges Bank
Norway
$210K +$210K +5,000 New
2 3
4
5 6