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Praxis Precision Medicines
PRAX

Overview Fund Activity

142 hedge funds and large institutions have $1.02B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 65 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
142
Holders Change
-7
Holders Change %
-4.7%
% of All Funds
1.9%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
65
Reduced
34
Closed
32
Calls
$26.3M
Puts
$15.5M
Net Calls
+$10.8M
Net Calls Change
+$15.8M

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
VR Adviser
New York
$0
2
Capital Research Global Investors
Capital Research Global Investors
California
$0
3
PA
Perceptive Advisors
New York
$31.7M
4
SCM
Soleus Capital Management
Connecticut
$40.7M
5
SCM
Silverarc Capital Management
Massachusetts
$421K
Name Holding Trade Value Shares
Change 		Shares
Change %
TLP
26
Tri Locum Partners
New York
$8.22M +$4.7M +111,773 +134%
5VM
27
5AM Venture Management
California
$7.15M – – –
VC
28
Vivo Capital
California
$7.05M +$7.05M +167,600 New
Charles Schwab
29
Charles Schwab
California
$6.41M +$478K +11,364 +8%
VCIM
30
Velan Capital Investment Management
Georgia
$6.28M -$1.5M -35,666 -19%
Alyeska Investment Group
31
Alyeska Investment Group
Illinois
$5.26M -$1.05M -25,000 -17%
Verition Fund Management
32
Verition Fund Management
Connecticut
$4.98M -$3.41M -81,175 -41%
BFM
33
Boothbay Fund Management
New York
$4.97M +$3.01M +71,495 +153%
SFM
34
Sphera Funds Management
Israel
$4.62M -$1.3M -30,903 -22%
SSA
35
Schonfeld Strategic Advisors
New York
$4.23M +$3.98M +94,628 +1,558%
UBS AM
36
UBS AM
Illinois
$4.08M +$415K +9,864 +11%
Barclays
37
Barclays
United Kingdom
$3.73M +$2.39M +56,956 +179%
UBS Group
38
UBS Group
Switzerland
$3.64M -$4.47M -106,375 -55%
PHS
39
PFM Health Sciences
California
$3.56M -$3.2M -76,153 -47%
ABG
40
Ally Bridge Group
New York
$3.4M -$618K -14,702 -15%
Pictet Asset Management
41
Pictet Asset Management
Switzerland
$3.33M +$23.3K +555 +0.7%
ACP
42
Acuta Capital Partners
California
$3.12M -$549K -13,054 -15%
KCM
43
Kennedy Capital Management
Missouri
$2.96M +$218K +5,180 +8%
HS
44
HighVista Strategies
Massachusetts
$2.83M +$1.18M +28,002 +71%
7IH
45
72 Investment Holdings
Connecticut
$2.77M – – –
TD Asset Management
46
TD Asset Management
Ontario, Canada
$2.69M +$1.13M +26,800 +72%
CS
47
Candriam SCA
Luxembourg
$2.68M – – –
EAM
48
Exome Asset Management
New York
$2.48M +$2.48M +59,002 New
Manulife (Manufacturers Life Insurance)
49
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.36M +$994K +23,639 +73%
Wellington Management Group
50
Wellington Management Group
Massachusetts
$2.35M +$215K +5,105 +10%
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