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Praxis Precision Medicines
PRAX

Overview Fund Activity

149 hedge funds and large institutions have $886M invested in Praxis Precision Medicines in 2025 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 47 increasing their positions, 51 reducing their positions, and 46 closing their positions.

Holders
149
Holders Change
-13
Holders Change %
-8.02%
% of All Funds
2.02%
Holding in Top 10
7
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.1%
New
34
Increased
47
Reduced
51
Closed
46
Calls
$17.8M
Puts
$22.8M
Net Calls
-$5.03M
Net Calls Change
-$50.5M

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$66M
2
SCM
2
Soleus Capital Management
Connecticut
$43.2M
3
DM
3
Deerfield Management
New York
$23.5M
4
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$58.3M
5
Bank of America
5
Bank of America
North Carolina
$17.4M

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$0
2
KCM
2
Kingdon Capital Management
New York
$0
3
PA
3
Perceptive Advisors
New York
$37.1M
4
SC
4
Stempoint Capital
New York
$0
5
Verition Fund Management
5
Verition Fund Management
Connecticut
$7.56M
Name Market Value Shares Shares
Change 		Shares
Change %
Goldman Sachs
26
Goldman Sachs
New York
$6.71M 177,264 -102,131 -37%
WP
27
Woodline Partners
California
$6.65M 175,727 +165,779 +1,666%
5VM
28
5AM Venture Management
California
$6.44M 170,000 – –
SCM
29
Silverarc Capital Management
Massachusetts
$6.29M 166,074 +93,558 +129%
Northern Trust
30
Northern Trust
Illinois
$6.26M 165,183 -2,407 -1%
PHS
31
PFM Health Sciences
California
$6.09M 160,866 +41,357 +35%
SI
32
Sofinnova Investments
California
$5.97M 157,640 +157,640 New
Alyeska Investment Group
33
Alyeska Investment Group
Illinois
$5.68M 150,000 -76,788 -34%
IC
34
Ikarian Capital
Texas
$5.51M 145,502 +145,502 New
Charles Schwab
35
Charles Schwab
California
$5.34M 141,080 -1,812 -1%
SFM
36
Sphera Funds Management
Israel
$5.33M 140,660 +49,077 +54%
Walleye Capital
37
Walleye Capital
New York
$4.99M 131,756 +42,143 +47%
SCM
38
Sio Capital Management
New York
$4.26M 112,500 +112,500 New
ABG
39
Ally Bridge Group
New York
$3.62M 95,582 +50,600 +112%
Aberdeen Group
40
Aberdeen Group
United Kingdom
$3.33M 87,903 +82,904 +1,658%
ACP
41
Acuta Capital Partners
California
$3.3M 87,141 +19,641 +29%
UBS AM
42
UBS AM
Illinois
$3.3M 87,081 +68,466 +368%
TLP
43
Tri Locum Partners
New York
$3.17M 83,659 +46,390 +124%
Pictet Asset Management
44
Pictet Asset Management
Switzerland
$2.98M 78,588 +33,161 +73%
FTM
45
First Turn Management
California
$2.72M 71,775 +26,239 +58%
Millennium Management
46
Millennium Management
New York
$2.62M 69,181 -81,711 -54%
7IH
47
72 Investment Holdings
Connecticut
$2.5M 65,933 – –
KCM
48
Kennedy Capital Management
Missouri
$2.47M 65,265 +65,265 New
CS
49
Candriam SCA
Luxembourg
$2.41M 63,671 -54,299 -46%
Citadel Advisors
50
Citadel Advisors
Florida
$2.36M 62,210 -30,980 -33%
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