|
1
|
EcoR1 Capital
San Francisco,
California
|
$435M
|
+$92.7M
|
+1,648,580
|
+29%
|
|
|
2
|
|
$398M
|
–
|
–
|
–
|
|
|
3
|
|
$362M
|
+$208M
|
+3,707,250
|
+151%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$312M
|
-$22.1M
|
-392,939
|
-7%
|
|
|
5
|
Avoro Capital Advisors
New York
|
$287M
|
-$100M
|
-1,779,826
|
-27%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$242M
|
+$152M
|
+2,711,656
|
+192%
|
|
|
7
|
|
$227M
|
+$18.1M
|
+321,891
|
+9%
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$188M
|
–
|
–
|
–
|
|
|
9
|
Simplicity Solutions
Minneapolis,
Minnesota
|
$184M
|
+$176M
|
+3,135,973
|
New
|
|
|
10
|
Braslyn
New Providence,
Bahamas
|
$184M
|
+$176M
|
+3,135,966
|
New
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$137M
|
-$23.7M
|
-421,700
|
-15%
|
|
|
12
|
Farallon Capital Management
San Francisco,
California
|
$119M
|
+$57.5M
|
+1,023,472
|
+102%
|
|
|
13
|
Alpine Associates Management
Palm Beach,
Florida
|
$111M
|
+$106M
|
+1,881,400
|
New
|
|
|
14
|
Tang Capital Management
San Diego,
California
|
$91.5M
|
+$77.5M
|
+1,378,059
|
+766%
|
|
|
15
|
Paradigm Biocapital Advisors
New York
|
$90.7M
|
-$7.03M
|
-125,000
|
-7%
|
|
|
16
|
Sio Capital Management
New York
|
$85.3M
|
+$81.6M
|
+1,451,925
|
New
|
|
|
17
|
Mangrove Partners
Greenwich,
Connecticut
|
$64.7M
|
+$61.9M
|
+1,101,736
|
New
|
|
|
18
|
Bank of New York Mellon
New York
|
$59.3M
|
+$46M
|
+817,394
|
+424%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$57.6M
|
+$5.55M
|
+98,803
|
+11%
|
|
|
20
|
Pentwater Capital Management
Naples,
Florida
|
$53M
|
+$50.7M
|
+902,632
|
New
|
|
|
21
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$49.1M
|
-$16.6M
|
-295,431
|
-26%
|
|
|
22
|
Magnetar Financial
Evanston,
Illinois
|
$49M
|
+$46.9M
|
+834,390
|
New
|
|
|
23
|
HSBC Holdings
London,
United Kingdom
|
$46M
|
+$44M
|
+783,092
|
New
|
|
|
24
|
|
$44.2M
|
+$18M
|
+319,661
|
+74%
|
|
|
25
|
AllianceBernstein
Nashville,
Tennessee
|
$43.4M
|
+$34.8M
|
+618,858
|
+517%
|
|
