|
1
|
Avoro Capital Advisors
New York
|
$237M
|
+$15.1M
|
+400,000
|
+9%
|
|
|
2
|
Aviva Holdings
New Providence,
Bahamas
|
$155M
|
–
|
–
|
–
|
|
|
3
|
Baker Bros. Advisors
New York
|
$124M
|
-$1.36M
|
-35,999
|
-1%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$97.9M
|
+$30.2M
|
+800,223
|
+67%
|
|
|
5
|
Cormorant Asset Management
Boston,
Massachusetts
|
$94.6M
|
–
|
–
|
–
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$77.2M
|
+$7.29M
|
+193,050
|
+14%
|
|
|
7
|
|
$71.5M
|
+$30.9M
|
+816,980
|
+129%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$69.3M
|
+$14.6M
|
+387,198
|
+38%
|
|
|
9
|
Deerfield Management
New York
|
$64.1M
|
+$41.7M
|
+1,103,365
|
+560%
|
|
|
10
|
Broadfin Capital
New York
|
$50.3M
|
-$16M
|
-423,770
|
-29%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$48.1M
|
+$10.5M
|
+278,115
|
+40%
|
|
|
12
|
Marshall Wace North America
New York
|
$39.7M
|
+$18.7M
|
+495,017
|
+160%
|
|
|
13
|
BVF Inc
San Francisco,
California
|
$36.7M
|
+$28.1M
|
+745,000
|
New
|
|
|
14
|
Farallon Capital Management
San Francisco,
California
|
$36.7M
|
+$17.9M
|
+473,500
|
+175%
|
|
|
15
|
Perceptive Advisors
New York
|
$35.2M
|
+$25.8M
|
+684,100
|
+2,352%
|
|
|
16
|
Janus Henderson Group
London,
|
$32.6M
|
+$25M
|
+662,039
|
New
|
|
|
17
|
Jennison Associates
New York
|
$30.3M
|
+$3.26M
|
+86,323
|
+16%
|
|
|
18
|
OppenheimerFunds
New York
|
$26.1M
|
+$20M
|
+528,845
|
New
|
|
|
19
|
Ghost Tree Capital
New York
|
$24.6M
|
+$8.97M
|
+237,500
|
+90%
|
|
|
20
|
Driehaus Capital Management
Chicago,
Illinois
|
$21.8M
|
+$16.7M
|
+441,470
|
New
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$15.5M
|
-$765K
|
-20,261
|
-6%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$13.4M
|
+$3.3M
|
+87,337
|
+47%
|
|
|
23
|
|
$12.5M
|
+$9.59M
|
+253,941
|
New
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$12.2M
|
+$7.07M
|
+187,191
|
+310%
|
|
|
25
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$11.8M
|
+$1.93M
|
+51,000
|
+27%
|
|
