|
1
|
Avoro Capital Advisors
New York
|
$808M
|
+$52.2M
|
+325,000
|
+7%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$668M
|
-$8.47M
|
-52,762
|
-1%
|
|
|
3
|
Perceptive Advisors
New York
|
$515M
|
-$46.3M
|
-288,607
|
-8%
|
|
|
4
|
Aviva Holdings
New Providence,
Bahamas
|
$507M
|
–
|
–
|
–
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$501M
|
+$147M
|
+917,067
|
+42%
|
|
|
6
|
|
$489M
|
-$248M
|
-1,546,086
|
-34%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$430M
|
-$19.7M
|
-122,998
|
-4%
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$323M
|
–
|
–
|
–
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$310M
|
+$62.5M
|
+389,279
|
+25%
|
|
|
10
|
|
$235M
|
+$20M
|
+124,300
|
+9%
|
|
|
11
|
Baker Bros. Advisors
New York
|
$228M
|
–
|
–
|
–
|
|
|
12
|
|
$204M
|
+$6.9M
|
+43,000
|
+4%
|
|
|
13
|
Franklin Resources
San Mateo,
California
|
$201M
|
+$40.3M
|
+251,126
|
+25%
|
|
|
14
|
Janus Henderson Group
London,
|
$173M
|
-$13.8M
|
-86,196
|
-7%
|
|
|
15
|
Farallon Capital Management
San Francisco,
California
|
$145M
|
+$8.03M
|
+50,000
|
+6%
|
|
|
16
|
|
$137M
|
+$20.1M
|
+125,000
|
+17%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$136M
|
-$35.1M
|
-218,493
|
-21%
|
|
|
18
|
Avidity Partners Management
Dallas,
Texas
|
$122M
|
+$44.5M
|
+277,300
|
+58%
|
|
|
19
|
Holocene Advisors
New York
|
$117M
|
+$66.5M
|
+414,251
|
+134%
|
|
|
20
|
Armistice Capital
New York
|
$107M
|
+$19.9M
|
+124,000
|
+23%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$91.9M
|
-$29.8M
|
-185,457
|
-25%
|
|
|
22
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$90.6M
|
+$53.6M
|
+333,765
|
+147%
|
|
|
23
|
Millennium Management
New York
|
$79.5M
|
+$59.4M
|
+369,794
|
+302%
|
|
|
24
|
EcoR1 Capital
San Francisco,
California
|
$75M
|
–
|
–
|
–
|
|
|
25
|
Citadel Advisors
Miami,
Florida
|
$73.9M
|
+$7.45M
|
+46,382
|
+11%
|
|
