|
1
|
Avoro Capital Advisors
New York
|
$204M
|
–
|
–
|
–
|
|
|
2
|
Aviva Holdings
New Providence,
Bahamas
|
$133M
|
–
|
–
|
–
|
|
|
3
|
Baker Bros. Advisors
New York
|
$107M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$93.2M
|
+$2.54M
|
+63,699
|
+3%
|
|
|
5
|
|
$87.1M
|
+$18.9M
|
+474,097
|
+30%
|
|
|
6
|
Cormorant Asset Management
Boston,
Massachusetts
|
$74.3M
|
-$2.32M
|
-58,301
|
-3%
|
|
|
7
|
Boxer Capital
San Diego,
California
|
$66.4M
|
–
|
–
|
–
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$65M
|
+$5.1M
|
+128,033
|
+9%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$60.7M
|
+$4.42K
|
+111
|
+0%
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$55.1M
|
+$16.9M
|
+425,000
|
+49%
|
|
|
11
|
Jennison Associates
New York
|
$51.6M
|
+$8.69M
|
+217,960
|
+22%
|
|
|
12
|
Janus Henderson Group
London,
|
$45.8M
|
+$2.11M
|
+52,955
|
+5%
|
|
|
13
|
Deerfield Management
New York
|
$37.1M
|
+$1.34M
|
+33,575
|
+4%
|
|
|
14
|
OppenheimerFunds
New York
|
$34.6M
|
+$11.6M
|
+291,544
|
+56%
|
|
|
15
|
BVF Inc
San Francisco,
California
|
$29.2M
|
-$1.37M
|
-34,471
|
-5%
|
|
|
16
|
EcoR1 Capital
San Francisco,
California
|
$27.5M
|
+$25.8M
|
+647,169
|
New
|
|
|
17
|
Credit Suisse
Zurich,
Switzerland
|
$19.5M
|
+$394K
|
+9,895
|
+2%
|
|
|
18
|
Putnam Investments
Boston,
Massachusetts
|
$18.5M
|
+$15.2M
|
+382,051
|
+702%
|
|
|
19
|
Ghost Tree Capital
New York
|
$17M
|
-$1.41M
|
-35,300
|
-8%
|
|
|
20
|
Wells Fargo
San Francisco,
California
|
$15M
|
+$3.58M
|
+89,959
|
+34%
|
|
|
21
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$14M
|
+$45.3K
|
+1,136
|
+0.3%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$13.3M
|
+$1.01M
|
+25,293
|
+9%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$11.6M
|
+$57.5K
|
+1,444
|
+0.5%
|
|
|
24
|
TIAA CREF Investment Management
New York
|
$11.5M
|
+$8.57M
|
+215,077
|
+385%
|
|
|
25
|
Amundi Asset Management US
Boston,
Massachusetts
|
$11.4M
|
+$3.3M
|
+82,900
|
+45%
|
|