|
1
|
|
$295M
|
+$82M
|
+2,295,529
|
+51%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$290M
|
+$39.7M
|
+1,111,111
|
+20%
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$250M
|
+$205M
|
+5,748,399
|
New
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$248M
|
+$25.8M
|
+721,357
|
+14%
|
|
|
5
|
|
$154M
|
+$8.08M
|
+226,292
|
+7%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$145M
|
-$2.44M
|
-68,443
|
-2%
|
|
|
7
|
Boxer Capital
San Diego,
California
|
$139M
|
+$42.9M
|
+1,201,440
|
+60%
|
|
|
8
|
Aviva Holdings
New Providence,
Bahamas
|
$137M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$120M
|
+$5.86M
|
+164,229
|
+6%
|
|
|
10
|
|
$107M
|
-$13.7M
|
-382,340
|
-13%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$106M
|
+$23.4M
|
+655,450
|
+37%
|
|
|
12
|
|
$88.2M
|
-$1.11M
|
-30,955
|
-2%
|
|
|
13
|
|
$85.3M
|
+$37.3M
|
+1,045,400
|
+114%
|
|
|
14
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$79.5M
|
+$36.3M
|
+1,016,858
|
+126%
|
|
|
15
|
Paradigm Biocapital Advisors
New York
|
$72.7M
|
+$8.01M
|
+224,354
|
+16%
|
|
|
16
|
Fidelity Investments
Boston,
Massachusetts
|
$66.6M
|
+$50.1M
|
+1,404,045
|
+1,134%
|
|
|
17
|
Camber Capital Management
Boston,
Massachusetts
|
$65.3M
|
-$10.7M
|
-300,000
|
-17%
|
|
|
18
|
Baker Bros. Advisors
New York
|
$61.4M
|
–
|
–
|
–
|
|
|
19
|
Armistice Capital
New York
|
$59.4M
|
-$93.3M
|
-2,613,902
|
-66%
|
|
|
20
|
Adage Capital Partners
Boston,
Massachusetts
|
$51.2M
|
+$42M
|
+1,175,000
|
New
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$49.3M
|
+$23.2M
|
+649,620
|
+135%
|
|
|
22
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$49.3M
|
+$341K
|
+9,560
|
+0.9%
|
|
|
23
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$45.3M
|
+$12.4M
|
+346,803
|
+50%
|
|
|
24
|
Farallon Capital Management
San Francisco,
California
|
$43.6M
|
+$35.7M
|
+1,001,000
|
New
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$38.9M
|
+$714K
|
+20,000
|
+2%
|
|
