|
1
|
Avoro Capital Advisors
New York
|
$885M
|
–
|
–
|
–
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$732M
|
+$552K
|
+3,434
|
+0.1%
|
|
|
3
|
Wellington Management Group
Boston,
Massachusetts
|
$609M
|
+$54.2M
|
+336,737
|
+11%
|
|
|
4
|
Perceptive Advisors
New York
|
$599M
|
+$32.5M
|
+201,847
|
+6%
|
|
|
5
|
Aviva Holdings
New Providence,
Bahamas
|
$555M
|
–
|
–
|
–
|
|
|
6
|
|
$470M
|
-$59.4M
|
-369,295
|
-12%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$469M
|
-$1.65M
|
-10,265
|
-0.4%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$374M
|
+$31M
|
+192,431
|
+10%
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$354M
|
–
|
–
|
–
|
|
|
10
|
Ameriprise
Minneapolis,
Minnesota
|
$280M
|
+$188M
|
+1,167,647
|
+280%
|
|
|
11
|
|
$264M
|
+$5.63M
|
+35,000
|
+2%
|
|
|
12
|
Baker Bros. Advisors
New York
|
$249M
|
–
|
–
|
–
|
|
|
13
|
|
$243M
|
+$17.5M
|
+109,000
|
+9%
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$227M
|
+$6.19M
|
+38,489
|
+3%
|
|
|
15
|
|
$212M
|
+$56.3M
|
+350,000
|
+41%
|
|
|
16
|
Avidity Partners Management
Dallas,
Texas
|
$188M
|
+$49.8M
|
+309,400
|
+41%
|
|
|
17
|
Janus Henderson Group
London,
|
$177M
|
-$11.6M
|
-71,966
|
-7%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$162M
|
+$12.2M
|
+75,935
|
+9%
|
|
|
19
|
Holocene Advisors
New York
|
$140M
|
+$11.3M
|
+70,171
|
+10%
|
|
|
20
|
Armistice Capital
New York
|
$126M
|
+$8.04M
|
+50,000
|
+8%
|
|
|
21
|
|
$122M
|
+$56.4M
|
+350,818
|
+104%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$99.2M
|
-$1.34M
|
-8,330
|
-1%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$99M
|
-$216K
|
-1,344
|
-0.2%
|
|
|
24
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$83.9M
|
+$18.8M
|
+116,561
|
+33%
|
|
|
25
|
EcoR1 Capital
San Francisco,
California
|
$82.1M
|
–
|
–
|
–
|
|
