|
1
|
Avoro Capital Advisors
New York
|
$373M
|
+$14.3M
|
+225,555
|
+4%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$305M
|
+$4.15M
|
+65,211
|
+1%
|
|
|
3
|
Aviva Holdings
New Providence,
Bahamas
|
$211M
|
–
|
–
|
–
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$195M
|
+$26.9M
|
+423,509
|
+17%
|
|
|
5
|
Perceptive Advisors
New York
|
$192M
|
+$30.9M
|
+486,153
|
+20%
|
|
|
6
|
|
$164M
|
+$147M
|
+2,318,853
|
+1,803%
|
|
|
7
|
|
$162M
|
-$24.6M
|
-387,272
|
-14%
|
|
|
8
|
Armistice Capital
New York
|
$137M
|
+$43.5M
|
+684,000
|
+50%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$135M
|
-$21.5M
|
-338,113
|
-14%
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$134M
|
–
|
–
|
–
|
|
|
11
|
|
$126M
|
+$20.4M
|
+321,166
|
+21%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$126M
|
+$28.8M
|
+453,050
|
+32%
|
|
|
13
|
Ameriprise
Minneapolis,
Minnesota
|
$98.2M
|
-$1.05M
|
-16,467
|
-1%
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$97.9M
|
+$19.5M
|
+307,184
|
+27%
|
|
|
15
|
Baker Bros. Advisors
New York
|
$94.6M
|
–
|
–
|
–
|
|
|
16
|
|
$73.8M
|
-$15.9M
|
-250,000
|
-19%
|
|
|
17
|
|
$73.2M
|
-$34.3M
|
-540,100
|
-33%
|
|
|
18
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$70.6M
|
-$37.7M
|
-592,686
|
-36%
|
|
|
19
|
Suvretta Capital Management
New York
|
$63.9M
|
+$28.1M
|
+441,655
|
+87%
|
|
|
20
|
|
$60.8M
|
+$49.6M
|
+780,024
|
+622%
|
|
|
21
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$57.2M
|
+$50.8M
|
+798,528
|
+1,495%
|
|
|
22
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$56.7M
|
+$18.1M
|
+285,243
|
+51%
|
|
|
23
|
Bank of Nova Scotia
Toronto,
Ontario, Canada
|
$56.5M
|
+$46.5M
|
+731,000
|
+665%
|
|
|
24
|
Janus Henderson Group
London,
|
$49.1M
|
-$13.4M
|
-209,946
|
-22%
|
|
|
25
|
Paradigm Biocapital Advisors
New York
|
$44.3M
|
+$35.7M
|
+561,585
|
+571%
|
|
