LYRA THERAPEUTICS INC
LYRA
LYRA was delisted on the 16th of March, 2026.
30 hedge funds and large institutions have $4.42M invested in LYRA THERAPEUTICS INC in 2025 Q2 according to their latest regulatory filings, with 8 funds opening new positions, 8 increasing their positions, 10 reducing their positions, and 35 closing their positions.
37% more capital invested
Capital invested by funds: $3.23M → $4.42M (+$1.19M)
36.5% more ownership
Funds ownership: 0.78% → 37.28% (+36%)
20% less repeat investments, than reductions
Existing positions increased: 8 | Existing positions reduced: 10
47% less funds holding
Funds holding: 57 → 30 (-27)
77% less first-time investments, than exits
New positions opened: 8 | Existing positions closed: 35
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
SM
Sabby Management
Miami Beach,
Florida
|
+$1.04M |
| 2 |
Bank of America
Charlotte,
North Carolina
|
+$233K |
| 3 |
State of Wisconsin Investment Board
Madison,
Wisconsin
|
+$87.1K |
| 4 |
Russell Investments Group
London,
United Kingdom
|
+$13.2K |
| 5 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
+$7.82K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
-$487K |
| 2 |
SB
Samsara BioCapital
Palo Alto,
California
|
-$176K |
| 3 |
Geode Capital Management
Boston,
Massachusetts
|
-$77.5K |
| 4 |
UBS Group
Zurich,
Switzerland
|
-$72K |
| 5 |
ACM
ADAR1 Capital Management
Austin,
Texas
|
-$67.3K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
51
T. Rowe Price Associates
Baltimore,
Maryland
| – | -$3K | -351 | Closed |
|
|
IIM
52
INTECH Investment Management
West Palm Beach,
Florida
| – | -$2.09K | -331 | Closed |
|
53
Squarepoint
New York
| – | -$1.93K | -306 | Closed |
|
54
SG Americas Securities
New York
| – | -$2K | -292 | Closed |
|
|
AHL
55
Abel Hall LLC
Baton Rouge,
Louisiana
| – | -$1.54K | -244 | Closed |
|
|
CWM
56
CIBC World Markets
New York
| – | -$1.36K | -215 | Closed |
|
57
ProShare Advisors
Bethesda,
Maryland
| – | -$1.32K | -210 | Closed |
|
|
SCA
58
Sassicaia Capital Advisers
Jericho,
New York
| – | -$1.26K | -200 | Closed |
|
59
Northwestern Mutual Wealth Management
Milwaukee,
Wisconsin
| – | -$758 | -120 | Closed |
|
|
AIP
60
Ameritas Investment Partners
Lincoln,
Nebraska
| – | -$599 | -95 | Closed |
|
61
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
| – | -$443 | -70 | Closed |
|
|
WSFS
62
Wilmington Savings Fund Society
Wilmington,
Delaware
| – | -$129 | -21 | Closed |
|
|
SCM
63
Sterling Capital Management
Charlotte,
North Carolina
| – | -$11 | -2 | Closed |
|
LYRA Hedge Fund Activity: Q2 2025 in Review
30 of the 7,597 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q2 2025, worth a combined $4.42M — up 37% from $3.23M a quarter earlier.
Sellers outnumbered buyers: 35 funds closed out of LYRA and 8 opened new positions — a net loss of 27 holders — while 10 trimmed existing stakes and 8 added.
The largest buyer was Sabby Management, opening a new position worth an estimated $1.04M. The largest seller was BlackRock, cutting an estimated $487K.
- 30 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q2 2025, down from 57 in Q1 2025.
- Funds reported $4.42M of LYRA THERAPEUTICS INC stock for Q2 2025, up 37% quarter-over-quarter.
- 8 funds opened new LYRA THERAPEUTICS INC positions in Q2 2025 and 35 closed out, a net change of -27 holders.
- The largest LYRA THERAPEUTICS INC buyer in Q2 2025 was Sabby Management, an estimated $1.04M added.
- The largest LYRA THERAPEUTICS INC seller in Q2 2025 was BlackRock, an estimated $487K sold.
Based on aggregated 13F filings for Q2 2025.