LYRA THERAPEUTICS INC
LYRA
LYRA was delisted on the 16th of March, 2026.
57 hedge funds and large institutions have $3.23M invested in LYRA THERAPEUTICS INC in 2025 Q1 according to their latest regulatory filings, with 6 funds opening new positions, 13 increasing their positions, 19 reducing their positions, and 3 closing their positions.
100% more first-time investments, than exits
New positions opened: 6 | Existing positions closed: 3
75% more call options, than puts
Call options by funds: $7K | Put options by funds: $4K
6% more funds holding
Funds holding: 54 → 57 (+3)
0.04% less ownership
Funds ownership: 0.82% → 0.78% (-0.04%)
32% less repeat investments, than reductions
Existing positions increased: 13 | Existing positions reduced: 19
42% less capital invested
Capital invested by funds: $5.54M → $3.23M (-$2.32M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Geode Capital Management
Boston,
Massachusetts
|
+$24.3K |
| 2 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$21.3K |
| 3 |
RhumbLine Advisers
Boston,
Massachusetts
|
+$8.69K |
| 4 |
Northern Trust
Chicago,
Illinois
|
+$8.67K |
| 5 |
Jane Street
New York
|
+$8.23K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
SB
Samsara BioCapital
Palo Alto,
California
|
-$108K |
| 2 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
-$70.6K |
| 3 |
Goldman Sachs
New York
|
-$34.7K |
| 4 |
Morgan Stanley
New York
|
-$28.2K |
| 5 |
JP Morgan Chase
New York
|
-$18.7K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
WSFS
51
Wilmington Savings Fund Society
Wilmington,
Delaware
| $129 | – | – | – |
|
52
Jones Financial Companies
Des Peres,
Missouri
| $69 | – | – | – |
|
53
Nisa Investment Advisors
St. Louis,
Missouri
| $63 | – | – | – |
|
|
EWA
54
EverSource Wealth Advisors
Birmingham,
Alabama
| $43 | +$47 | +5 | +250% |
|
|
SCM
55
Sterling Capital Management
Charlotte,
North Carolina
| $11 | – | – | – |
|
|
56
Qube Research & Technologies (QRT)
London,
United Kingdom
| – | -$70.6K | -6,843 | Closed |
|
57
Bank of Montreal
Toronto,
Ontario, Canada
| – | -$11.2K | -1,083 | Closed |
|
|
VF
58
Virtu Financial
New York
| – | -$9K | -841 | Closed |
|
59
Simplex Trading
Chicago,
Illinois
| – | +$178 | +19 | +271% |
|
LYRA Hedge Fund Activity: Q1 2025 in Review
57 of the 7,460 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q1 2025, worth a combined $3.23M — down 42% from $5.54M a quarter earlier.
Buyers outnumbered sellers: 6 funds opened new LYRA positions and 3 closed out — a net gain of 3 holders — while 13 added to existing stakes and 19 trimmed.
The largest buyer was Geode Capital Management, adding an estimated $24.3K. The largest seller was Samsara BioCapital, cutting an estimated $108K.
- 57 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q1 2025, up from 54 in Q4 2024.
- Funds reported $3.23M of LYRA THERAPEUTICS INC stock for Q1 2025, down 42% quarter-over-quarter.
- 6 funds opened new LYRA THERAPEUTICS INC positions in Q1 2025 and 3 closed out, a net change of +3 holders.
- The largest LYRA THERAPEUTICS INC buyer in Q1 2025 was Geode Capital Management, an estimated $24.3K added.
- The largest LYRA THERAPEUTICS INC seller in Q1 2025 was Samsara BioCapital, an estimated $108K sold.
Based on aggregated 13F filings for Q1 2025.