LYRA THERAPEUTICS INC
LYRA
LYRA was delisted on the 16th of March, 2026.
35 hedge funds and large institutions have $59.9M invested in LYRA THERAPEUTICS INC in 2022 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 10 increasing their positions, 6 reducing their positions, and 6 closing their positions.
1,800% more call options, than puts
Call options by funds: $38K | Put options by funds: $2K
67% more repeat investments, than reductions
Existing positions increased: 10 | Existing positions reduced: 6
0.01% less ownership
Funds ownership: 1.2% → 1.2% (-0.01%)
5% less funds holding
Funds holding: 37 → 35 (-2)
33% less first-time investments, than exits
New positions opened: 4 | Existing positions closed: 6
38% less capital invested
Capital invested by funds: $96M → $59.9M (-$36.1M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Ensign Peak Advisors
Salt Lake City,
Utah
|
+$946K |
| 2 |
BCM
Bridgeway Capital Management
Houston,
Texas
|
+$356K |
| 3 |
AFM
Anson Funds Management
Dallas,
Texas
|
+$155K |
| 4 |
Bank of America
Charlotte,
North Carolina
|
+$28.1K |
| 5 |
BAM
Belpointe Asset Management
Reno,
Nevada
|
+$14.6K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PVI
Pura Vida Investments
New York
|
-$1.4M |
| 2 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
-$99K |
| 3 |
Bank of New York Mellon
New York
|
-$98K |
| 4 |
Millennium Management
New York
|
-$95K |
| 5 |
TSS
Two Sigma Securities
New York
|
-$64K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
AWM
26
Ameliora Wealth Management
Zurich,
Switzerland
| $2.35K | – | – | – |
|
|
WAM
27
Worth Asset Management
Dallas,
Texas
| $2.04K | – | – | – |
|
28
Osaic Holdings
Scottsdale,
Arizona
| $2K | – | – | – |
|
29
Royal Bank of Canada
Toronto,
Ontario, Canada
| $2K | +$1.39K | +7 | +233% |
|
|
S
30
SignatureFD
Atlanta,
Georgia
| $1.57K | – | – | – |
|
31
US Bancorp
Minneapolis,
Minnesota
| $1.57K | – | – | – |
|
32
Fidelity Investments
Boston,
Massachusetts
| $1.41K | +$1.78K | +9 | New |
|
|
CA
33
CoreCap Advisors
Southfield,
Michigan
| $393 | +$594 | +3 | New |
|
34
Wells Fargo
San Francisco,
California
| $355 | – | – | – |
|
|
IRC
35
Investors Research Corp
Atlanta,
Georgia
| $47 | – | – | – |
|
36
Morgan Stanley
New York
| $3 | – | – | – |
|
|
37
Bank of New York Mellon
New York
| – | -$98K | -390 | Closed |
|
|
38
Millennium Management
New York
| – | -$95K | -378 | Closed |
|
|
TSS
39
Two Sigma Securities
New York
| – | -$64K | -255 | Closed |
|
|
HWM
40
HighMark Wealth Management
St. Paul,
Minnesota
| – | -$20K | -80 | Closed |
|
41
BNP Paribas Financial Markets
Paris,
France
| – | -$150 | -1 | Closed |
|
LYRA Hedge Fund Activity: Q4 2022 in Review
35 of the 6,222 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q4 2022, worth a combined $59.9M — down 38% from $96M a quarter earlier.
Sellers outnumbered buyers: 6 funds closed out of LYRA and 4 opened new positions — a net loss of 2 holders — while 6 trimmed existing stakes and 10 added.
The largest buyer was Ensign Peak Advisors, adding an estimated $946K. The largest seller was Pura Vida Investments, cutting an estimated $1.4M.
- 35 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q4 2022, down from 37 in Q3 2022.
- Funds reported $59.9M of LYRA THERAPEUTICS INC stock for Q4 2022, down 38% quarter-over-quarter.
- 4 funds opened new LYRA THERAPEUTICS INC positions in Q4 2022 and 6 closed out, a net change of -2 holders.
- The largest LYRA THERAPEUTICS INC buyer in Q4 2022 was Ensign Peak Advisors, an estimated $946K added.
- The largest LYRA THERAPEUTICS INC seller in Q4 2022 was Pura Vida Investments, an estimated $1.4M sold.
Based on aggregated 13F filings for Q4 2022.