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Disc Medicine
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Overview Fund Activity

148 hedge funds and large institutions have $1.8B invested in Disc Medicine in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 68 increasing their positions, 35 reducing their positions, and 31 closing their positions.

Holders
148
Holders Change
-9
Holders Change %
-5.73%
% of All Funds
1.99%
Holding in Top 10
9
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+12.5%
% of All Funds
0.12%
New
25
Increased
68
Reduced
35
Closed
31
Calls
$23.4M
Puts
$1.11M
Net Calls
+$22.3M
Net Calls Change
+$21M

Top Buyers

1
WP
1
Woodline Partners
California
$45.9M
2
LGM
2
Logos Global Management
California
$37.1M
3
FTM
3
First Turn Management
California
$15.9M
4
BBA
4
Baker Bros. Advisors
New York
$17.9M
5
SCM
5
Sio Capital Management
New York
$15.1M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$75.8M
2
BCLSI
2
Bain Capital Life Sciences Investors
Massachusetts
$30.9M
3
SCM
3
Silverarc Capital Management
Massachusetts
$0
4
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$0
5
PA
5
Perceptive Advisors
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
New York State Common Retirement Fund
76
New York State Common Retirement Fund
New York
$892K 16,852 +10,576 +169%
Invesco
77
Invesco
Georgia
$891K 16,817 +2,983 +22%
Deutsche Bank
78
Deutsche Bank
Germany
$885K 16,717 +2,012 +14%
Citigroup
79
Citigroup
New York
$853K 16,109 -26,866 -63%
Mirae Asset Global ETFs Holdings
80
Mirae Asset Global ETFs Holdings
Hong Kong
$799K 15,041 -97 -0.6%
MIM
81
MetLife Investment Management
New Jersey
$787K 14,854 +1,400 +10%
HIS
82
Harvest Investment Services
Illinois
$758K 14,316 -1,066 -7%
Walleye Capital
83
Walleye Capital
New York
$745K 14,064 -8,011 -36%
AQR Capital Management
84
AQR Capital Management
Connecticut
$723K 13,649 +13,649 New
State of Wisconsin Investment Board
85
State of Wisconsin Investment Board
Wisconsin
$683K 12,889 +906 +8%
TRSOTSOK
86
Teachers Retirement System of the State of Kentucky
Kentucky
$681K 12,851 -1,777 -12%
UOC
87
UBS O'Connor
Illinois
$652K 12,317 -1,304 -10%
IIM
88
INTECH Investment Management
Florida
$647K 12,222 +1,274 +12%
Bank of Montreal
89
Bank of Montreal
Ontario, Canada
$582K 10,988 +5,137 +88%
LPC
90
Lion Point Capital
New York
$561K 10,600 – –
First Trust Advisors
91
First Trust Advisors
Illinois
$543K 10,246 +10,246 New
YIH
92
Y-Intercept (HK)
Hong Kong
$497K 9,382 +9,382 New
State Board of Administration of Florida Retirement System
93
State Board of Administration of Florida Retirement System
Florida
$483K 9,129 +5,079 +125%
Universal-Beteiligungs- und Servicegesellschaft
94
Universal-Beteiligungs- und Servicegesellschaft
Germany
$391K 7,376 +985 +15%
SI
95
Sofinnova Investments
California
$387K 7,312 -173 -2%
LCM
96
Legato Capital Management
California
$383K 7,228 +7,228 New
CUAMC
97
China Universal Asset Management Company
China
$368K 6,956 +22 +0.3%
HS
98
HighVista Strategies
Massachusetts
$357K 6,733 +275 +4%
PA
99
Profund Advisors
Maryland
$356K 6,714 -446 -6%
VOYA Investment Management
100
VOYA Investment Management
Georgia
$355K 6,695 +744 +13%
2 3
4
5 6