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Disc Medicine

215 hedge funds and large institutions have $3.13B invested in Disc Medicine in 2026 Q2 according to their latest regulatory filings, with 39 funds opening new positions, 75 increasing their positions, 63 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

461% more call options, than puts

Call options by funds: $26.6M | Put options by funds: $4.75M

77% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 22

19% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 63

17% more capital invested

Capital invested by funds: $2.67B → $3.13B (+$457M)

17% more funds holding in top 10

Funds holding in top 10: 67 (+1)

6% more funds holding

Funds holding: 203215 (+12)

2.06% more ownership

Funds ownership: 109.8%111.86% (+2.1%)

Holders
215
Holders Change
+12
Holders Change %
+5.91%
% of All Funds
2.6%
Holding in Top 10
7
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+16.67%
% of All Funds
0.08%
New
39
Increased
75
Reduced
63
Closed
22
Calls
$26.6M
Puts
$4.75M
Net Calls
+$21.9M
Net Calls Change
+$3.6M
Name Holding Trade Value Shares
Change
Change in
Stake
PAI
26
Palo Alto Investors
California
$30.5M +$1.03M +14,927 +4%
EAM
27
Eventide Asset Management
Massachusetts
$28.9M +$5.43K +79 +0%
Pictet Asset Management
28
Pictet Asset Management
Switzerland
$28.2M -$112K -1,630 -0.4%
Assenagon Asset Management
29
Assenagon Asset Management
Luxembourg
$28.1M -$11.1M -162,089 -30%
Loomis, Sayles & Company
30
Loomis, Sayles & Company
Massachusetts
$27.9M +$4.44M +64,642 +20%
FCMV
31
Foresite Capital Management V
California
$27.4M
O
32
OrbiMed
New York
$26.2M -$48.8M -710,015 -67%
BBA
33
Baker Bros. Advisors
New York
$25.6M
Vanguard Portfolio Management
34
Vanguard Portfolio Management
Pennsylvania
$20.6M +$2.38M +34,599 +14%
OCA
35
Octagon Capital Advisors
New York
$19.7M
Northern Trust
36
Northern Trust
Illinois
$19.4M +$1.22M +17,795 +7%
Charles Schwab
37
Charles Schwab
California
$18.8M +$425K +6,187 +2%
CC
38
Checkpoint Capital
California
$17.6M -$3.2M -46,536 -16%
Vanguard Fiduciary Trust
39
Vanguard Fiduciary Trust
Pennsylvania
$16.5M +$533K +7,762 +4%
Citadel Advisors
40
Citadel Advisors
Florida
$15.3M +$7.65M +111,378 +114%
Bank of New York Mellon
41
Bank of New York Mellon
New York
$15M -$16.6K -241 -0.1%
BNP Paribas Financial Markets
42
BNP Paribas Financial Markets
France
$13.5M +$3.91M +56,958 +45%
CCM
43
Catalio Capital Management
New York
$11.7M +$2.5M +36,406 +30%
SI
44
Sofinnova Investments
California
$10.7M +$4.67M +67,919 +87%
BCLSI
45
Bain Capital Life Sciences Investors
Massachusetts
$10.3M
Two Sigma Investments
46
Two Sigma Investments
New York
$10M +$9.4M +136,750 New
Bank of America
47
Bank of America
North Carolina
$9.88M -$2.18M -31,664 -19%
Alyeska Investment Group
48
Alyeska Investment Group
Illinois
$9.14M
Ensign Peak Advisors
49
Ensign Peak Advisors
Utah
$8.93M -$4.77M -69,376 -36%
UBS AM
50
UBS AM
Illinois
$8.35M +$221K +3,219 +3%

IRON Hedge Fund Activity: Q2 2026 in Review

215 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q2 2026, worth a combined $3.13B — up 17% from $2.67B a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new IRON positions and 22 closed out — a net gain of 17 holders — while 75 added to existing stakes and 63 trimmed.

The largest buyer was Vestal Point Capital, adding an estimated $58.4M. The largest seller was OrbiMed, cutting an estimated $48.8M.

  • 215 institutional investors held Disc Medicine (IRON) as of Q2 2026, up from 203 in Q1 2026.
  • Funds reported $3.13B of Disc Medicine stock for Q2 2026, up 17% quarter-over-quarter.
  • 39 funds opened new Disc Medicine positions in Q2 2026 and 22 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q2 2026 was Vestal Point Capital, an estimated $58.4M added.
  • The largest Disc Medicine seller in Q2 2026 was OrbiMed, an estimated $48.8M sold.

Based on aggregated 13F filings for Q2 2026.