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Ionis Pharmaceuticals

425 hedge funds and large institutions have $11B invested in Ionis Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 113 funds opening new positions, 133 increasing their positions, 115 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

16% more repeat investments, than reductions

Existing positions increased: 133 | Existing positions reduced: 115

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

0.95% less ownership

Funds ownership: 106.09%105.14% (-0.95%)

Holders
425
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$170M
Puts
$74.8M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
CSS
151
Cubist Systematic Strategies
Connecticut
$3.18M
Ohio Public Employees Retirement System (OPERS)
152
Ohio Public Employees Retirement System (OPERS)
Ohio
$3.18M
PHK
153
Point72 Hong Kong
Hong Kong
$3.11M
DFCM
154
Dark Forest Capital Management
Puerto Rico
$3.02M
Zurich Cantonal Bank
155
Zurich Cantonal Bank
Switzerland
$2.96M
Canada Life
156
Canada Life
Manitoba, Canada
$2.96M
HSBC Holdings
157
HSBC Holdings
United Kingdom
$2.95M
ASRS
158
Arizona State Retirement System
Arizona
$2.93M
BA
159
Bridgewater Associates
Connecticut
$2.85M
FAM
160
Fred Alger Management
New York
$2.77M
Dimensional Fund Advisors
161
Dimensional Fund Advisors
Texas
$2.76M
NSEDCP
162
NJ State Employees Deferred Compensation Plan
New Jersey
$2.75M
GD
163
Grandfield & Dodd
New York
$2.46M
LP
164
LMR Partners
United Kingdom
$2.46M
PCM
165
Prelude Capital Management
New York
$2.44M
Verition Fund Management
166
Verition Fund Management
Connecticut
$2.43M
OCM
167
One Capital Management
California
$2.38M
FFL
168
Future Fund LLC
Illinois
$2.37M
QCM
169
Quantinno Capital Management
New York
$2.36M
SLG
170
Stanley-Laman Group
Pennsylvania
$2.34M
GC
171
Guggenheim Capital
Illinois
$2.31M
William Blair & Company
172
William Blair & Company
Illinois
$2.25M
Pathstone Holdings
173
Pathstone Holdings
New Jersey
$2.2M
ET
174
Entropy Technologies
New York
$2.15M
GAM
175
Gotham Asset Management
New York
$2.1M