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Ionis Pharmaceuticals
IONS

Overview Fund Activity

336 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 114 increasing their positions, 107 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
336
Holders Change
-9
Holders Change %
-2.61%
% of All Funds
5.42%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
114
Reduced
107
Closed
52
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.47M
Net Calls Change
-$7.76M

Top Buyers

1
O
OrbiMed
New York
$75.3M
2
DTC
Deep Track Capital
Connecticut
$45.5M
3
TBC
Tweedy, Browne Co
Connecticut
$134M
4
Vanguard Group
Vanguard Group
Pennsylvania
$512M
5
Macquarie Group
Macquarie Group
Australia
$56.3M

Top Sellers

1
BI
BVF Inc
California
$42.4M
2
AIM
ARK Investment Management
Florida
$101M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$162M
4
WP
Woodline Partners
California
$0
5
Goldman Sachs
Goldman Sachs
New York
$34.8M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$805M +$618K +16,360 +0.1%
Vanguard Group
2
Vanguard Group
Pennsylvania
$512M +$28M +740,671 +6%
T. Rowe Price Investment Management
3
T. Rowe Price Investment Management
Maryland
$441M +$19.7M +521,564 +5%
BG
4
Bellevue Group
Switzerland
$368M +$10.6M +280,500 +3%
BlackRock
5
BlackRock
New York
$343M +$5.42M +143,495 +2%
ClearBridge Investments
6
ClearBridge Investments
New York
$205M -$13.2M -348,250 -6%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$162M -$19.1M -504,701 -11%
State Street
8
State Street
Massachusetts
$159M +$17.3M +457,774 +12%
TBC
9
Tweedy, Browne Co
Connecticut
$134M +$30.9M +818,148 +30%
AIM
10
ARK Investment Management
Florida
$101M -$39.3M -1,039,569 -28%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$76M +$4.21M +111,580 +6%
O
12
OrbiMed
New York
$75.3M +$46.3M +1,224,700 +159%
CCM
13
Camber Capital Management
Massachusetts
$72.7M – – –
First Trust Advisors
14
First Trust Advisors
Illinois
$67.3M -$11.2M -296,327 -14%
Macquarie Group
15
Macquarie Group
Australia
$56.3M +$24.8M +657,646 +79%
Norges Bank
16
Norges Bank
Norway
$49M +$4M +105,896 +9%
Charles Schwab
17
Charles Schwab
California
$47.4M +$2.04M +53,922 +4%
DTC
18
Deep Track Capital
Connecticut
$45.5M +$45.5M +1,205,773 New
Renaissance Technologies
19
Renaissance Technologies
New York
$44.5M +$11.8M +311,100 +36%
BI
20
BVF Inc
California
$42.4M -$66.1M -1,751,144 -61%
Swedbank
21
Swedbank
Sweden
$38.6M – – –
JPMorgan Chase & Co
22
JPMorgan Chase & Co
New York
$36.6M +$1.57M +41,558 +4%
Morgan Stanley
23
Morgan Stanley
New York
$35.4M +$9.07M +240,171 +34%
Goldman Sachs
24
Goldman Sachs
New York
$34.8M -$13.9M -368,154 -29%
Thrivent Financial for Lutherans
25
Thrivent Financial for Lutherans
Minnesota
$34.7M +$410K +10,853 +1%
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