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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$805M +$688K +16,360 +0.1%
Vanguard Group
2
Vanguard Group
Pennsylvania
$512M +$31.2M +740,671 +6%
T. Rowe Price Investment Management
3
T. Rowe Price Investment Management
Maryland
$441M +$21.9M +521,564 +5%
BG
4
Bellevue Group
Switzerland
$368M +$11.8M +280,500 +3%
BlackRock
5
BlackRock
New York
$343M +$6.04M +143,495 +2%
ClearBridge Investments
6
ClearBridge Investments
New York
$205M -$14.6M -348,250 -6%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$162M -$21.2M -504,701 -11%
State Street
8
State Street
Massachusetts
$159M +$19.3M +457,774 +12%
TBC
9
Tweedy, Browne Co
Connecticut
$134M +$34.4M +818,148 +30%
AIM
10
ARK Investment Management
Florida
$101M -$43.7M -1,039,569 -28%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$76M +$4.69M +111,580 +6%
O
12
OrbiMed
New York
$75.3M +$51.5M +1,224,700 +159%
CCM
13
Camber Capital Management
Massachusetts
$72.7M
First Trust Advisors
14
First Trust Advisors
Illinois
$67.3M -$12.5M -296,327 -14%
Macquarie Group
15
Macquarie Group
Australia
$56.3M +$27.7M +657,646 +79%
Norges Bank
16
Norges Bank
Norway
$49M +$4.45M +105,896 +9%
Charles Schwab
17
Charles Schwab
California
$47.4M +$2.27M +53,922 +4%
DTC
18
Deep Track Capital
Connecticut
$45.5M +$50.7M +1,205,773 New
Renaissance Technologies
19
Renaissance Technologies
New York
$44.5M +$13.1M +311,100 +36%
BI
20
BVF Inc
California
$42.4M -$73.7M -1,751,144 -61%
Swedbank
21
Swedbank
Sweden
$38.6M
JP Morgan Chase
22
JP Morgan Chase
New York
$36.6M +$1.75M +41,558 +4%
Morgan Stanley
23
Morgan Stanley
New York
$35.4M +$10.1M +240,171 +34%
Goldman Sachs
24
Goldman Sachs
New York
$34.8M -$15.5M -368,154 -29%
Thrivent Financial for Lutherans
25
Thrivent Financial for Lutherans
Minnesota
$34.7M +$456K +10,853 +1%

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.