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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$1.84B +$38.2M +484,536 +2%
Capital World Investors
2
Capital World Investors
California
$1.59B +$255M +3,225,070 +18%
BlackRock
3
BlackRock
New York
$784M -$16.2M -205,387 -2%
VPM
4
Vanguard Portfolio Management
Pennsylvania
$586M +$616M +7,808,902 New
VCM
5
Vanguard Capital Management
Pennsylvania
$535M +$562M +7,118,330 New
Wellington Management Group
6
Wellington Management Group
Massachusetts
$480M +$10.4M +131,491 +2%
T. Rowe Price Investment Management
7
T. Rowe Price Investment Management
Maryland
$462M -$233M -2,948,992 -32%
Two Sigma Investments
8
Two Sigma Investments
New York
$440M +$252M +3,198,983 +120%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$305M +$65.9M +835,483 +27%
State Street
10
State Street
Massachusetts
$300M +$1.63M +20,699 +0.5%
Royal Bank of Canada
11
Royal Bank of Canada
Ontario, Canada
$285M +$212M +2,683,018 +240%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$227M +$2.95M +37,411 +1%
JP Morgan Chase
13
JP Morgan Chase
New York
$171M +$4.64M +58,775 +3%
TBC
14
Tweedy, Browne Co
Connecticut
$171M -$14.9M -189,305 -8%
Artisan Partners
15
Artisan Partners
Wisconsin
$155M +$69.2M +876,892 +74%
BBA
16
Baker Bros. Advisors
New York
$154M +$20.2M +255,886 +14%
DM
17
Deerfield Management
New York
$149M
DTC
18
Deep Track Capital
Connecticut
$146M +$19.7M +250,000 +15%
BG
19
Bellevue Group
Switzerland
$137M -$235M -2,983,534 -62%
Goldman Sachs
20
Goldman Sachs
New York
$128M +$66.6M +843,881 +99%
American Century Companies
21
American Century Companies
Missouri
$125M +$3.69M +46,697 +3%
Charles Schwab
22
Charles Schwab
California
$119M +$3.27M +41,425 +3%
Franklin Resources
23
Franklin Resources
California
$118M +$20M +253,678 +19%
UBS AM
24
UBS AM
Illinois
$111M +$6.87M +87,065 +6%
Pictet Asset Management
25
Pictet Asset Management
Switzerland
$107M +$1.3M +16,504 +1%