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Ionis Pharmaceuticals

364 hedge funds and large institutions have $5.55B invested in Ionis Pharmaceuticals in 2021 Q1 according to their latest regulatory filings, with 53 funds opening new positions, 127 increasing their positions, 111 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed

73% more call options, than puts

Call options by funds: $56.3M | Put options by funds: $32.5M

14% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 111

1.74% more ownership

Funds ownership: 85.94%87.67% (+1.7%)

5% less funds holding

Funds holding: 382364 (-18)

18% less capital invested

Capital invested by funds: $6.8B → $5.55B (-$1.25B)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

21% less first-time investments, than exits

New positions opened: 53 | Existing positions closed: 67

Holders
364
Holders Change
-18
Holders Change %
-4.71%
% of All Funds
6.39%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.07%
New
53
Increased
127
Reduced
111
Closed
67
Calls
$56.3M
Puts
$32.5M
Net Calls
+$23.8M
Net Calls Change
-$29.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$948M +$8.69M +155,862 +0.7%
Vanguard Group
2
Vanguard Group
Pennsylvania
$567M +$20.1M +359,761 +3%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$566M -$29.8M -534,911 -4%
BlackRock
4
BlackRock
New York
$441M +$3.24M +58,060 +0.6%
BG
5
Bellevue Group
Switzerland
$404M -$3.67M -65,858 -0.7%
ClearBridge Investments
6
ClearBridge Investments
New York
$333M +$27.2M +487,820 +7%
AIM
7
ARK Investment Management
Florida
$231M +$153M +2,742,717 +114%
State Street
8
State Street
Massachusetts
$153M -$28.1M -503,757 -13%
Invesco
9
Invesco
Georgia
$106M -$57.2M -1,025,435 -30%
JP Morgan Chase
10
JP Morgan Chase
New York
$88.3M +$5.01M +89,891 +5%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$77.6M +$3.18M +56,942 +3%
WRF
12
Waddell & Reed Financial
Kansas
$72.6M -$29.9M -536,823 -25%
BI
13
BVF Inc
California
$61.3M
First Trust Advisors
14
First Trust Advisors
Illinois
$52.5M -$12.2M -219,122 -16%
Wells Fargo
15
Wells Fargo
California
$52M +$350K +6,281 +0.5%
Swedbank
16
Swedbank
Sweden
$50.4M +$62.5M +1,121,067 New
CCM
17
Camber Capital Management
Massachusetts
$45M +$55.8M +1,000,000 New
N
18
Nuveen
North Carolina
$42.7M +$18.5M +330,826 +53%
American Century Companies
19
American Century Companies
Missouri
$42.4M -$16.8M -301,852 -24%
Sumitomo Mitsui Trust Group
20
Sumitomo Mitsui Trust Group
Japan
$40.5M +$7.62M +136,617 +18%
Northern Trust
21
Northern Trust
Illinois
$37.8M +$891K +15,971 +2%
Norges Bank
22
Norges Bank
Norway
$36.3M +$2.62M +47,063 +6%
Goldman Sachs
23
Goldman Sachs
New York
$33.5M -$16.7M -299,144 -29%
Rockefeller Capital Management
24
Rockefeller Capital Management
New York
$33M +$10M +179,807 +32%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$32.1M -$4.79M -85,800 -11%

IONS Hedge Fund Activity: Q1 2021 in Review

364 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q1 2021, worth a combined $5.55B — down 18% from $6.8B a quarter earlier.

Sellers outnumbered buyers: 67 funds closed out of IONS and 53 opened new positions — a net loss of 14 holders — while 111 trimmed existing stakes and 127 added.

The largest buyer was ARK Investment Management, adding an estimated $153M. The largest seller was Invesco, cutting an estimated $57.2M.

  • 364 institutional investors held Ionis Pharmaceuticals (IONS) as of Q1 2021, down from 382 in Q4 2020.
  • Funds reported $5.55B of Ionis Pharmaceuticals stock for Q1 2021, down 18% quarter-over-quarter.
  • 53 funds opened new Ionis Pharmaceuticals positions in Q1 2021 and 67 closed out, a net change of -14 holders.
  • The largest Ionis Pharmaceuticals buyer in Q1 2021 was ARK Investment Management, an estimated $153M added.
  • The largest Ionis Pharmaceuticals seller in Q1 2021 was Invesco, an estimated $57.2M sold.

Based on aggregated 13F filings for Q1 2021.