Vanguard Group’s Ionis Pharmaceuticals IONS Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q4
$1.3B Sell
16,440,459
-41,271
-0.3% -$3.11M 0.02% 616
2025
Q3
$1.08B Sell
16,481,730
-233,116
-1% -$11.4M 0.02% 669
2025
Q2
$660M Buy
16,714,846
+330,912
+2% +$10.8M 0.01% 863
2025
Q1
$494M Sell
16,383,934
-88,605
-0.5% -$2.9M 0.01% 999
2024
Q4
$576M Buy
16,472,539
+1,416,781
+9% +$53M 0.01% 956
2024
Q3
$603M Buy
15,055,758
+1,210,046
+9% +$56.3M 0.01% 925
2024
Q2
$660M Buy
13,845,712
+415,256
+3% +$17M 0.01% 823
2024
Q1
$582M Sell
13,430,456
-773,025
-5% -$36.8M 0.01% 916
2023
Q4
$719M Sell
14,203,481
-298,544
-2% -$14.3M 0.02% 775
2023
Q3
$658M Sell
14,502,025
-21,241
-0.1% -$876K 0.02% 762
2023
Q2
$596M Buy
14,523,266
+547,476
+4% +$21M 0.01% 829
2023
Q1
$499M Buy
13,975,790
+429,096
+3% +$16.1M 0.01% 908
2022
Q4
$512M Buy
13,546,694
+740,671
+6% +$31.2M 0.01% 870
2022
Q3
$566M Buy
12,806,023
+605,747
+5% +$25.5M 0.02% 759
2022
Q2
$452M Buy
12,200,276
+101,242
+0.8% +$3.82M 0.01% 921
2022
Q1
$448M Buy
12,099,034
+91,958
+0.8% +$3.01M 0.01% 1043
2021
Q4
$365M Buy
12,007,076
+207,067
+2% +$6.52M 0.01% 1198
2021
Q3
$396M Sell
11,800,009
-855,820
-7% -$32.2M 0.01% 1128
2021
Q2
$505M Buy
12,655,829
+51,680
+0.4% +$2.02M 0.01% 983
2021
Q1
$567M Buy
12,604,149
+359,761
+3% +$20.1M 0.02% 884
2020
Q4
$692M Buy
12,244,388
+254,358
+2% +$12.7M 0.02% 728
2020
Q3
$569M Sell
11,990,030
-316,221
-3% -$17.6M 0.02% 723
2020
Q2
$726M Buy
12,306,251
+252,690
+2% +$14.1M 0.03% 601
2020
Q1
$570M Buy
12,053,561
+87,169
+0.7% +$4.86M 0.02% 623
2019
Q4
$723M Sell
11,966,392
-248,083
-2% -$14.8M 0.02% 664
2019
Q3
$732M Sell
12,214,475
-642,390
-5% -$41.9M 0.03% 630
2019
Q2
$826M Buy
12,856,865
+383,350
+3% +$27.1M 0.03% 586
2019
Q1
$1.01B Buy
12,473,515
+644,127
+5% +$41.6M 0.04% 496
2018
Q4
$639M Buy
11,829,388
+738,090
+7% +$37.6M 0.03% 601
2018
Q3
$572M Buy
11,091,298
+157,770
+1% +$7.41M 0.02% 724
2018
Q2
$456M Buy
10,933,528
+558,132
+5% +$24.7M 0.02% 828
2018
Q1
$457M Buy
10,375,396
+269,184
+3% +$13.7M 0.02% 794
2017
Q4
$508M Buy
10,106,212
+162,261
+2% +$8.9M 0.02% 745
2017
Q3
$504M Buy
9,943,951
+88,791
+0.9% +$4.65M 0.02% 721
2017
Q2
$501M Buy
9,855,160
+417,364
+4% +$19.4M 0.02% 702
2017
Q1
$379M Buy
9,437,796
+384,830
+4% +$17.3M 0.02% 820
2016
Q4
$433M Buy
9,052,966
+259,814
+3% +$10.3M 0.02% 718
2016
Q3
$322M Sell
8,793,152
-1,631
-0% -$51K 0.02% 817
2016
Q2
$205M Buy
8,794,783
+349,172
+4% +$11.3M 0.01% 1041
2016
Q1
$342M Buy
8,445,611
+194,861
+2% +$7.91M 0.02% 739
2015
Q4
$511M Sell
8,250,750
-557,026
-6% -$30.1M 0.03% 568
2015
Q3
$356M Buy
8,807,776
+227,426
+3% +$11.8M 0.03% 697
2015
Q2
$494M Buy
8,580,350
+567,324
+7% +$36.1M 0.03% 596
2015
Q1
$510M Buy
8,013,026
+741,155
+10% +$50.3M 0.03% 577
2014
Q4
$449M Buy
7,271,871
+14,355
+0.2% +$708K 0.03% 594
2014
Q3
$282M Sell
7,257,516
-12,028
-0.2% -$426K 0.02% 771
2014
Q2
$250M Sell
7,269,544
-516,802
-7% -$16.3M 0.02% 845
2014
Q1
$336M Buy
7,786,346
+104,400
+1% +$5.06M 0.03% 662
2013
Q4
$306M Buy
7,681,946
+346,234
+5% +$12.3M 0.03% 673
2013
Q3
$275M Buy
7,335,712
+634,403
+9% +$19M 0.03% 680
2013
Q2
$180M Buy
+6,701,309
New +$143M 0.02% 825

Other funds holding IONS

Vanguard Group's IONS Position: Q4 2025 in Review

Vanguard Group reduced its Ionis Pharmaceuticals (IONS) stake by 0.25% in Q4 2025, selling an estimated $3.11M and leaving 16,440,459 shares worth $1.3B. The position accounts for 0.02% of the portfolio, ranked #616.

Vanguard Group first reported a position in IONS in Q2 2013 and has held it in 51 quarters since. 491 funds tracked by Wall St. Rank hold IONS as of Q4 2025.

  • Vanguard Group held 16,440,459 shares of Ionis Pharmaceuticals worth $1.3B as of Q4 2025.
  • Vanguard Group sold 41,271 Ionis Pharmaceuticals shares in Q4 2025, an estimated $3.11M.
  • Ionis Pharmaceuticals made up 0.02% of Vanguard Group's portfolio in Q4 2025, its #616 holding.
  • Vanguard Group first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 51 quarters since.
  • 491 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.