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Ionis Pharmaceuticals

354 hedge funds and large institutions have $5.61B invested in Ionis Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 58 funds opening new positions, 119 increasing their positions, 120 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 50

1.72% more ownership

Funds ownership: 99.9%101.62% (+1.7%)

0% more funds holding

Funds holding: 353354 (+1)

1% less repeat investments, than reductions

Existing positions increased: 119 | Existing positions reduced: 120

11% less capital invested

Capital invested by funds: $6.3B → $5.61B (-$692M)

15% less call options, than puts

Call options by funds: $26.1M | Put options by funds: $30.5M

Holders
354
Holders Change
+1
Holders Change %
+0.28%
% of All Funds
4.66%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
58
Increased
119
Reduced
120
Closed
50
Calls
$26.1M
Puts
$30.5M
Net Calls
-$4.46M
Net Calls Change
-$17.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$793M +$7.85M +209,962 +0.9%
Vanguard Group
2
Vanguard Group
Pennsylvania
$576M +$53M +1,416,781 +9%
T. Rowe Price Investment Management
3
T. Rowe Price Investment Management
Maryland
$495M +$40.5K +1,083 +0%
BlackRock
4
BlackRock
New York
$408M +$31.9M +852,525 +8%
Capital World Investors
5
Capital World Investors
California
$401M +$136M +3,637,041 +46%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$303M -$2.38M -63,639 -0.7%
BG
7
Bellevue Group
Switzerland
$275M -$213K -5,700 -0.1%
State Street
8
State Street
Massachusetts
$190M +$21.5M +576,276 +12%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$134M -$14.3M -383,233 -9%
TBC
10
Tweedy, Browne Co
Connecticut
$114M -$7.69M -205,813 -6%
O
11
OrbiMed
New York
$98.5M +$18.4M +492,900 +21%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$94M +$706K +18,890 +0.7%
Citadel Advisors
13
Citadel Advisors
Florida
$75.7M +$66M +1,764,765 +440%
DTC
14
Deep Track Capital
Connecticut
$67.6M -$9.95M -266,072 -12%
UBS Group
15
UBS Group
Switzerland
$67M +$65.4M +1,749,728 +1,042%
Macquarie Group
16
Macquarie Group
Australia
$61.9M -$3.74M -100,063 -5%
Norges Bank
17
Norges Bank
Norway
$59.9M -$11.7M -312,399 -15%
ClearBridge Investments
18
ClearBridge Investments
New York
$56.6M -$3.15M -84,173 -5%
Charles Schwab
19
Charles Schwab
California
$51.8M +$1.44M +38,420 +3%
Two Sigma Advisers
20
Two Sigma Advisers
New York
$47.2M +$628K +16,800 +1%
Morgan Stanley
21
Morgan Stanley
New York
$46.5M +$728K +19,478 +1%
BNP Paribas Asset Management
22
BNP Paribas Asset Management
France
$37.8M +$11.2M +300,620 +39%
TD Asset Management
23
TD Asset Management
Ontario, Canada
$36.7M -$1.61M -43,000 -4%
AIM
24
ARK Investment Management
Florida
$35.8M -$13.4M -359,009 -26%
Two Sigma Investments
25
Two Sigma Investments
New York
$32.2M +$88.3K +2,362 +0.3%

IONS Hedge Fund Activity: Q4 2024 in Review

354 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2024, worth a combined $5.61B — down 11% from $6.3B a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new IONS positions and 50 closed out — a net gain of 8 holders — while 119 added to existing stakes and 120 trimmed.

The largest buyer was Capital World Investors, adding an estimated $136M. The largest seller was Artisan Partners, cutting an estimated $74.3M.

  • 354 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2024, up from 353 in Q3 2024.
  • Funds reported $5.61B of Ionis Pharmaceuticals stock for Q4 2024, down 11% quarter-over-quarter.
  • 58 funds opened new Ionis Pharmaceuticals positions in Q4 2024 and 50 closed out, a net change of +8 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2024 was Capital World Investors, an estimated $136M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2024 was Artisan Partners, an estimated $74.3M sold.

Based on aggregated 13F filings for Q4 2024.