ClearBridge Investments’s Ionis Pharmaceuticals IONS Stock Holding History

ClearBridge Investments’s Portfolio IONS Stock Details IONS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-2,715	Closed	-$215K	–	718
2025 Q4	$215K	Buy	+2,715	New	+$204K	﹤0.01%	689
2025 Q1	–	Sell	-1,618,220	Closed	-$56.6M	–	724
2024 Q4	$56.6M	Sell	1,618,220 -84,173	-5%	-$3.15M	0.05%	302
2024 Q3	$68.2M	Sell	1,702,393 -457,877	-21%	-$21.3M	0.05%	286
2024 Q2	$103M	Sell	2,160,270 -2,305,921	-52%	-$94.6M	0.08%	225
2024 Q1	$194M	Sell	4,466,191 -241,289	-5%	-$11.5M	0.15%	147
2023 Q4	$238M	Sell	4,707,480 -133,215	-3%	-$6.38M	0.2%	123
2023 Q3	$220M	Sell	4,840,695 -346,509	-7%	-$14.3M	0.21%	118
2023 Q2	$213M	Sell	5,187,204 -204,377	-4%	-$7.85M	0.19%	129
2023 Q1	$193M	Sell	5,391,581 -34,061	-0.6%	-$1.28M	0.18%	133
2022 Q4	$205M	Sell	5,425,642 -348,250	-6%	-$14.6M	0.2%	121
2022 Q3	$255M	Sell	5,773,892 -231,926	-4%	-$9.77M	0.26%	103
2022 Q2	$222M	Sell	6,005,818 -470,215	-7%	-$17.7M	0.21%	119
2022 Q1	$240M	Buy	6,476,033 +593,051	+10%	+$19.4M	0.18%	133
2021 Q4	$179M	Sell	5,882,982 -1,444,340	-20%	-$45.5M	0.12%	161
2021 Q3	$246M	Buy	7,327,322 +511,721	+8%	+$19.3M	0.18%	129
2021 Q2	$272M	Sell	6,815,601 -587,366	-8%	-$23M	0.19%	118
2021 Q1	$333M	Buy	7,402,967 +487,820	+7%	+$27.2M	0.25%	100
2020 Q4	$391M	Sell	6,915,147 -358,218	-5%	-$17.9M	0.3%	90
2020 Q3	$345M	Sell	7,273,365 -388,859	-5%	-$21.6M	0.3%	87
2020 Q2	$452M	Sell	7,662,224 -372,040	-5%	-$20.7M	0.41%	68
2020 Q1	$380M	Buy	8,034,264 +86,688	+1%	+$4.83M	0.41%	69
2019 Q4	$484M	Sell	7,947,576 -1,343,348	-14%	-$80M	0.4%	74
2019 Q3	$557M	Sell	9,290,924 -211,108	-2%	-$13.8M	0.49%	64
2019 Q2	$611M	Buy	9,502,032 +3,722	+0%	+$263K	0.53%	53
2019 Q1	$771M	Sell	9,498,310 -882,009	-8%	-$56.9M	0.68%	35
2018 Q4	$561M	Buy	10,380,319 +143,380	+1%	+$7.31M	0.57%	44
2018 Q3	$528M	Sell	10,236,939 -583,181	-5%	-$27.4M	0.45%	63
2018 Q2	$451M	Sell	10,820,120 -99,989	-0.9%	-$4.43M	0.37%	84
2018 Q1	$481M	Sell	10,920,109 -64,709	-0.6%	-$3.29M	0.45%	69
2017 Q4	$553M	Sell	10,984,818 -455,033	-4%	-$25M	0.51%	57
2017 Q3	$580M	Sell	11,439,851 -388,030	-3%	-$20.3M	0.56%	45
2017 Q2	$602M	Sell	11,827,881 -45,298	-0.4%	-$2.11M	0.59%	39
2017 Q1	$477M	Sell	11,873,179 -179,404	-1%	-$8.06M	0.48%	58
2016 Q4	$576M	Buy	12,052,583 +1,224,208	+11%	+$48.4M	0.63%	37
2016 Q3	$397M	Sell	10,828,375 -438,752	-4%	-$13.7M	0.45%	60
2016 Q2	$262M	Buy	11,267,127 +142,579	+1%	+$4.6M	0.31%	93
2016 Q1	$451M	Buy	11,124,548 +1,649,844	+17%	+$67M	0.54%	49
2015 Q4	$587M	Buy	9,474,704 +89,624	+1%	+$4.84M	0.68%	31
2015 Q3	$379M	Sell	9,385,080 -37,922	-0.4%	-$1.96M	0.45%	58
2015 Q2	$542M	Sell	9,423,002 -163,155	-2%	-$10.4M	0.57%	40
2015 Q1	$610M	Buy	9,586,157 +551,637	+6%	+$37.4M	0.63%	36
2014 Q4	$558M	Buy	9,034,520 +45,764	+0.5%	+$2.26M	0.59%	38
2014 Q3	$349M	Buy	8,988,756 +749,398	+9%	+$26.6M	0.38%	78
2014 Q2	$284M	Buy	8,239,358 +895,096	+12%	+$28.2M	0.32%	97
2014 Q1	$317M	Buy	7,344,262 +146,601	+2%	+$7.11M	0.38%	80
2013 Q4	$287M	Sell	7,197,661 -17,907	-0.2%	-$638K	0.36%	87
2013 Q3	$271M	Buy	7,215,568 +393,043	+6%	+$11.7M	0.38%	84
2013 Q2	$183M	Buy	+6,822,525	New	+$145M	0.28%	106

Other funds holding IONS

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

T. Rowe Price Investment Management Baltimore, Maryland $145B AUM 22.78% 1-Year Est. Return

Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

ClearBridge Investments's IONS Position: Q1 2026 in Review

ClearBridge Investments sold out of Ionis Pharmaceuticals (IONS) in Q1 2026, closing a stake of 2,715 shares — an estimated $215K sold.

ClearBridge Investments first reported a position in IONS in Q2 2013 and held it in 48 quarters. The position peaked at $771M in Q1 2019. 493 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

ClearBridge Investments reported no remaining Ionis Pharmaceuticals position as of Q1 2026 after selling out during the quarter.
ClearBridge Investments sold 2,715 Ionis Pharmaceuticals shares in Q1 2026, an estimated $215K.
ClearBridge Investments first reported a position in Ionis Pharmaceuticals in Q2 2013 and held it in 48 quarters.
ClearBridge Investments's Ionis Pharmaceuticals position peaked at $771M in Q1 2019.
493 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on ClearBridge Investments's 13F filing for Q1 2026, filed 13 May 2026.