Millennium Management’s Ionis Pharmaceuticals IONS Stock Holding History
Bought
Maintained
Sold
| Quarter | Market Value | Status | Shares |
Change in Stake | Trade Value | Portfolio Weight | Portfolio Position | |
|---|---|---|---|---|---|---|---|---|
|
2026
Q1 | $79M | Buy |
1,051,506
+958,244
| +1,027% | +$75.6M | 0.03% | 563 |
|
|
2025
Q4 | $7.38M | Sell |
93,262
-686,308
| -88% | -$51.7M | ﹤0.01% | 2585 |
|
|
2025
Q3 | $51M | Sell |
779,570
-1,869,957
| -71% | -$91.3M | 0.02% | 859 |
|
|
2025
Q2 | $105M | Buy |
2,649,527
+2,014,157
| +317% | +$65.9M | 0.05% | 371 |
|
|
2025
Q1 | $19.2M | Sell |
635,370
-138,845
| -18% | -$4.55M | 0.01% | 1560 |
|
|
2024
Q4 | $27.1M | Buy |
774,215
+343,492
| +80% | +$12.8M | 0.01% | 1270 |
|
|
2024
Q3 | $17.3M | Buy |
430,723
+302,508
| +236% | +$14.1M | 0.01% | 1680 |
|
|
2024
Q2 | $6.11M | Sell |
128,215
-454,964
| -78% | -$18.7M | ﹤0.01% | 2535 |
|
|
2024
Q1 | $25.3M | Sell |
583,179
-307,146
| -34% | -$14.6M | 0.01% | 1357 |
|
|
2023
Q4 | $45M | Buy |
890,325
+453,202
| +104% | +$21.7M | 0.02% | 869 |
|
|
2023
Q3 | $19.8M | Buy |
437,123
+18,210
| +4% | +$751K | 0.01% | 1449 |
|
|
2023
Q2 | $17.2M | Buy |
418,913
+373,550
| +823% | +$14.4M | 0.01% | 1526 |
|
|
2023
Q1 | $1.62M | Sell |
45,363
-70,143
| -61% | -$2.63M | ﹤0.01% | 3635 |
|
|
2022
Q4 | $4.36M | Buy |
115,506
+96,577
| +510% | +$4.06M | ﹤0.01% | 2932 |
|
|
2022
Q3 | $837K | Sell |
18,929
-301,686
| -94% | -$12.7M | ﹤0.01% | 4486 |
|
|
2022
Q2 | $11.9M | Buy |
320,615
+129,424
| +68% | +$4.88M | 0.01% | 1833 |
|
|
2022
Q1 | $7.08M | Sell |
191,191
-1,431,947
| -88% | -$46.9M | ﹤0.01% | 2557 |
|
|
2021
Q4 | $49.4M | Buy |
1,623,138
+1,340,284
| +474% | +$42.2M | 0.03% | 729 |
|
|
2021
Q3 | $9.49M | Sell |
282,854
-512,988
| -64% | -$19.3M | 0.01% | 2126 |
|
|
2021
Q2 | $31.7M | Buy |
795,842
+164,578
| +26% | +$6.45M | 0.02% | 860 |
|
|
2021
Q1 | $28.4M | Buy |
631,264
+100,675
| +19% | +$5.61M | 0.02% | 831 |
|
|
2020
Q4 | $30M | Buy |
530,589
+421,632
| +387% | +$21M | 0.02% | 775 |
|
|
2020
Q3 | $5.17K | Buy |
108,957
+95,588
| +715% | +$5.31M | 0.01% | 1809 |
|
|
2020
Q2 | $788K | Sell |
13,369
-58,223
| -81% | -$3.24M | ﹤0.01% | 3133 |
|
|
2020
Q1 | $3.38M | Buy |
71,592
+61,528
| +611% | +$3.43M | 0.01% | 1635 |
|
|
2019
Q4 | $608K | Sell |
10,064
-45,141
| -82% | -$2.69M | ﹤0.01% | 3264 |
|
|
2019
Q3 | $3.31M | Sell |
55,205
-135,739
| -71% | -$8.85M | 0.01% | 2106 |
|
|
2019
Q2 | $12.3M | Buy |
190,944
+25,905
| +16% | +$1.83M | 0.02% | 1104 |
|
|
2019
Q1 | $13.4M | Buy |
165,039
+81,561
| +98% | +$5.26M | 0.02% | 1066 |
|
|
2018
Q4 | $4.51M | Sell |
83,478
-44,849
| -35% | -$2.29M | 0.01% | 1660 |
|
|
2018
Q3 | $6.62M | Sell |
128,327
-53,607
| -29% | -$2.52M | 0.01% | 1605 |
|
|
2018
Q2 | $7.58M | Sell |
181,934
-90,903
| -33% | -$4.03M | 0.01% | 1509 |
|
|
2018
Q1 | $12M | Buy |
272,837
+76,920
| +39% | +$3.91M | 0.02% | 1215 |
|
|
2017
Q4 | $9.86M | Buy |
195,917
+2,874
| +1% | +$158K | 0.01% | 1331 |
|
|
2017
Q3 | $9.79M | Buy |
193,043
+96,324
| +100% | +$5.05M | 0.01% | 1262 |
|
|
2017
Q2 | $4.92M | Sell |
96,719
-152,610
| -61% | -$7.11M | 0.01% | 1521 |
|
|
2017
Q1 | $10M | Buy |
249,329
+244,954
| +5,599% | +$11M | 0.02% | 1021 |
|
|
2016
Q4 | $209K | Sell |
4,375
-1,601,931
| -100% | -$63.4M | ﹤0.01% | 3066 |
|
|
2016
Q3 | $58.9M | Buy |
+1,606,306
| New | +$50.3M | 0.1% | 217 |
|
|
2016
Q2 | – | Sell |
-1,078,089
| Closed | -$43.7M | – | 3359 |
|
|
2016
Q1 | $43.7M | Buy |
+1,078,089
| New | +$43.8M | 0.11% | 211 |
|
|
2015
Q4 | – | Sell |
-180,814
| Closed | -$7.31M | – | 3586 |
|
|
2015
Q3 | $7.31M | Sell |
180,814
-187,242
| -51% | -$9.69M | 0.01% | 1117 |
|
|
2015
Q2 | $21.2M | Buy |
368,056
+361,256
| +5,313% | +$23M | 0.04% | 600 |
|
|
2015
Q1 | $433K | Buy |
+6,800
| New | +$461K | ﹤0.01% | 2828 |
|
|
2014
Q3 | – | Sell |
-198,138
| Closed | -$6.83M | – | 3838 |
|
|
2014
Q2 | $6.83M | Sell |
198,138
-10,243
| -5% | -$323K | 0.02% | 1018 |
|
|
2014
Q1 | $9M | Buy |
208,381
+168,381
| +421% | +$8.16M | 0.03% | 870 |
|
|
2013
Q4 | $1.59M | Sell |
40,000
-220,133
| -85% | -$7.84M | 0.01% | 1980 |
|
|
2013
Q3 | $9.77M | Sell |
260,133
-554,185
| -68% | -$16.6M | 0.03% | 692 |
|
|
2013
Q2 | $21.9M | Buy |
+814,318
| New | +$17.3M | 0.07% | 269 |
|
Other funds holding IONS
VPM
VCM
Millennium Management's IONS Position: Q1 2026 in Review
Millennium Management increased its Ionis Pharmaceuticals (IONS) stake by 1,027% in Q1 2026, buying an estimated $75.6M and bringing the position to 1,051,506 shares worth $79M. The position accounts for 0.03% of the portfolio, ranked #563.
Millennium Management first reported a position in IONS in Q2 2013 and has held it in 48 quarters since. The position peaked at $105M in Q2 2025. 493 funds tracked by Wall St. Rank hold IONS as of Q1 2026.
- Millennium Management held 1,051,506 shares of Ionis Pharmaceuticals worth $79M as of Q1 2026.
- Millennium Management bought 958,244 Ionis Pharmaceuticals shares in Q1 2026, an estimated $75.6M.
- Ionis Pharmaceuticals made up 0.03% of Millennium Management's portfolio in Q1 2026, its #563 holding.
- Millennium Management first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 48 quarters since.
- Millennium Management's Ionis Pharmaceuticals position peaked at $105M in Q2 2025.
- 493 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.
Based on Millennium Management's 13F filing for Q1 2026, filed 15 May 2026.