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Tweedy, Browne Co’s Ionis Pharmaceuticals IONS Stock Holding History

Tweedy, Browne Co’s Portfolio IONS Stock Details IONS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$181M Buy
2,280,311
+4,686
+0.2% +$353K 13.7% 2
2026
Q1 		$171M Sell
2,275,625
-189,305
-8% -$14.9M 13.57% 2
2025
Q4 		$195M Sell
2,464,930
-436,286
-15% -$32.9M 15.74% 1
2025
Q3 		$190M Buy
2,901,216
+9,268
+0.3% +$452K 16.48% 1
2025
Q2 		$114M Sell
2,891,948
-91,570
-3% -$3M 10.6% 3
2025
Q1 		$90M Sell
2,983,518
-265,345
-8% -$8.69M 7.98% 5
2024
Q4 		$114M Sell
3,248,863
-205,813
-6% -$7.69M 7.66% 6
2024
Q3 		$138M Hold
3,454,676
– – 6.6% 6
2024
Q2 		$165M Hold
3,454,676
– – 7.57% 5
2024
Q1 		$150M Hold
3,454,676
– – 7.03% 5
2023
Q4 		$175M Sell
3,454,676
-55,497
-2% -$2.66M 8.53% 5
2023
Q3 		$159M Sell
3,510,173
-30,685
-0.9% -$1.27M 8.52% 4
2023
Q2 		$145M Sell
3,540,858
-188
-0% -$7.22K 7.63% 5
2023
Q1 		$127M Sell
3,541,046
-90
-0% -$3.38K 6.89% 6
2022
Q4 		$134M Buy
3,541,136
+818,148
+30% +$34.4M 7.12% 4
2022
Q3 		$120M Sell
2,722,988
-3,790
-0.1% -$160K 5.3% 7
2022
Q2 		$101M Sell
2,726,778
-198,324
-7% -$7.48M 4.13% 8
2022
Q1 		$108M Buy
+2,925,102
New +$95.7M 3.5% 8

Other funds holding IONS

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
Royal Bank of Canada
Royal Bank of Canada Toronto, Ontario, Canada $672B AUM 33.48% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $153B AUM 38.14% 1-Year Est. Return

Tweedy, Browne Co's IONS Position: Q2 2026 in Review

Tweedy, Browne Co increased its Ionis Pharmaceuticals (IONS) stake by 0.21% in Q2 2026, buying an estimated $353K and bringing the position to 2,280,311 shares worth $181M. The position accounts for 13.7% of the portfolio, ranked #2.

Tweedy, Browne Co first reported a position in IONS in Q1 2022 and has held it in 18 quarters since. The position peaked at $195M in Q4 2025. 514 funds tracked by Wall St. Rank hold IONS as of Q2 2026.

  • Tweedy, Browne Co held 2,280,311 shares of Ionis Pharmaceuticals worth $181M as of Q2 2026.
  • Tweedy, Browne Co bought 4,686 Ionis Pharmaceuticals shares in Q2 2026, an estimated $353K.
  • Ionis Pharmaceuticals made up 13.7% of Tweedy, Browne Co's portfolio in Q2 2026, its #2 holding.
  • Tweedy, Browne Co first reported a position in Ionis Pharmaceuticals in Q1 2022 and has held it in 18 quarters since.
  • Tweedy, Browne Co's Ionis Pharmaceuticals position peaked at $195M in Q4 2025.
  • 514 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q2 2026.

Based on Tweedy, Browne Co's 13F filing for Q2 2026, filed 7 Aug 2026.