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Ionis Pharmaceuticals

490 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 177 increasing their positions, 155 reducing their positions, and 66 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more funds holding

Funds holding:

0.75% less ownership

Funds ownership: 105.2%104.44% (-0.75%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$517M)

Holders
490
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$141M
Puts
$144M
Net Calls
Net Calls Change

Top Buyers

1 +$255M
2 +$252M
3 +$212M
4
Millennium Management
Millennium Management
New York
+$75.6M
5
Artisan Partners
Artisan Partners
Wisconsin
+$69.2M

Top Sellers

1 -$235M
2 -$233M
3 -$94.1M
4
Nomura Holdings
Nomura Holdings
Japan
-$58M
5
TLP
Tri Locum Partners
New York
-$44.1M
Name Holding Trade Value Shares
Change
Change in
Stake
PWPS
326
Pinnacle Wealth Planning Services
Ohio
$316K
Rockefeller Capital Management
327
Rockefeller Capital Management
New York
$312K
Mirae Asset Global ETFs Holdings
328
Mirae Asset Global ETFs Holdings
Hong Kong
$310K
IA
329
Inspire Advisors
Idaho
$309K
Wealth Enhancement Advisory Services
330
Wealth Enhancement Advisory Services
Minnesota
$309K
IB
331
Intrust Bank
Kansas
$305K
OL
332
Optas LLC
Texas
$303K
PCIA
333
Prime Capital Investment Advisors
Kansas
$298K
CAM
334
Congress Asset Management
Massachusetts
$296K
SA
335
Sanctuary Advisors
Indiana
$294K
AC
336
AXQ Capital
New Jersey
$289K
HighTower Advisors
337
HighTower Advisors
Illinois
$285K
Mackenzie Financial
338
Mackenzie Financial
Ontario, Canada
$285K
AB
339
ANB Bank
Colorado
$283K
Carson Wealth (CWM LLC)
340
Carson Wealth (CWM LLC)
Nebraska
$279K
SPIA
341
Steward Partners Investment Advisory
New York
$273K
BAM
342
Berkshire Asset Management
Pennsylvania
$273K
GFM
343
GF Fund Management
China
$273K
MG
344
Marex Group
$271K
Westfield Capital Management
345
Westfield Capital Management
Massachusetts
$263K
EFG
346
Everhart Financial Group
Ohio
$261K
PWM
347
Perigon Wealth Management
California
$258K
ECSS
348
Eurizon Capital SGR SpA
$256K
MPPW
349
Mitchell & Pahl Private Wealth
Oklahoma
$245K
NL
350
NWAM LLC
Washington
$243K