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Ionis Pharmaceuticals

490 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 177 increasing their positions, 155 reducing their positions, and 66 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more funds holding

Funds holding:

0.75% less ownership

Funds ownership: 105.2%104.44% (-0.75%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$517M)

Holders
490
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$141M
Puts
$144M
Net Calls
Net Calls Change

Top Buyers

1 +$255M
2 +$252M
3 +$212M
4
Millennium Management
Millennium Management
New York
+$75.6M
5
Artisan Partners
Artisan Partners
Wisconsin
+$69.2M

Top Sellers

1 -$235M
2 -$233M
3 -$94.1M
4
Nomura Holdings
Nomura Holdings
Japan
-$58M
5
TLP
Tri Locum Partners
New York
-$44.1M
Name Holding Trade Value Shares
Change
Change in
Stake
PA
376
Parallel Advisors
California
$141K
AAM
377
Advisors Asset Management
Colorado
$141K
EWA
378
EverSource Wealth Advisors
Alabama
$135K
GI
379
GAMMA Investing
California
$133K
VCM
380
Versant Capital Management
Arizona
$117K
SCM
381
Sterling Capital Management
North Carolina
$107K
SAM
382
Smartleaf Asset Management
Massachusetts
$103K
IAIM
383
International Assets Investment Management
Florida
$91.7K
SI
384
Stephens Inc
Arkansas
$91.4K
SS
385
Sunbelt Securities
Texas
$76.1K
IA
386
IFP Advisors
Florida
$71.3K
MCM
387
MAI Capital Management
Ohio
$70.6K
Los Angeles Capital Management
388
Los Angeles Capital Management
California
$52.6K
RFP
389
Root Financial Partners
California
$51.1K
HNB
390
Huntington National Bank
Ohio
$51.1K
QCG
391
Quadrant Capital Group
Ohio
$46.3K
ASN
392
Advisory Services Network
Georgia
$45.4K
AIC
393
Archer Investment Corporation
Indiana
$45.1K
AF
394
Advisornet Financial
Minnesota
$43K
HI
395
Harbour Investments
Wisconsin
$41K
AF
396
Allworth Financial
California
$39.2K
BC
397
Bayforest Capital
United Kingdom
$31K
MG
398
Mather Group
Illinois
$30.8K
OWP
399
ORG Wealth Partners
Texas
$30K
CCWM
400
Cassaday & Co Wealth Management
Virginia
$30K