IONS icon

Ionis Pharmaceuticals

490 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 177 increasing their positions, 155 reducing their positions, and 66 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more funds holding

Funds holding:

0.75% less ownership

Funds ownership: 105.2%104.44% (-0.75%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$517M)

Holders
490
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$141M
Puts
$144M
Net Calls
Net Calls Change

Top Buyers

1 +$255M
2 +$252M
3 +$212M
4
Millennium Management
Millennium Management
New York
+$75.6M
5
Artisan Partners
Artisan Partners
Wisconsin
+$69.2M

Top Sellers

1 -$235M
2 -$233M
3 -$94.1M
4
Nomura Holdings
Nomura Holdings
Japan
-$58M
5
TLP
Tri Locum Partners
New York
-$44.1M
Name Holding Trade Value Shares
Change
Change in
Stake
GSWM
401
Golden State Wealth Management
California
$28.2K
DWP
402
Destiny Wealth Partners
Florida
$28.2K
ERSOT
403
Employees Retirement System of Texas
Texas
$28K
CA
404
CoreCap Advisors
Michigan
$27.8K
HHCP
405
Hilton Head Capital Partners
South Carolina
$26.5K
BBHC
406
Brown Brothers Harriman & Co
New York
$25.6K
SL
407
Salomon & Ludwin
Virginia
$24.8K
SIS
408
Sound Income Strategies
Florida
$22.5K
EB
409
Eastern Bank
Massachusetts
$22.5K
SGK
410
Steigerwald Gordon & Koch
Virginia
$22.2K
CAL
411
Capital Advisors Ltd
Ohio
$22K
NS
412
NBC Securities
Alabama
$20.5K
PFBT
413
Parkside Financial Bank & Trust
Missouri
$19.4K
MIM
414
MTM Investment Management
South Carolina
$19.4K
HFM
415
Harvest Fund Management
China
$18K
WIM
416
Westside Investment Management
California
$17.3K
CMA
417
Cedar Mountain Advisors
Oregon
$16.7K
ACM
418
Aster Capital Management
United Arab Emirates
$16.6K
GTAM
419
Global Trust Asset Management
Florida
$16.4K
UB
420
UMB Bank
Missouri
$16.1K
TPWA
421
Twin Peaks Wealth Advisors
California
$16.1K
EC
422
Elequin Capital
New York
$15.6K
MASM
423
MH & Associates Securities Management
California
$15K
AUB
424
Atlantic Union Bankshares
Virginia
$15K
CI
425
CX Institutional
Indiana
$15K