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Ionis Pharmaceuticals
IONS

Overview Fund Activity

360 hedge funds and large institutions have $6.67B invested in Ionis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 81 funds opening new positions, 121 increasing their positions, 108 reducing their positions, and 58 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
360
Holders Change
+21
Holders Change %
+6.19%
% of All Funds
4.83%
Holding in Top 10
12
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+100%
% of All Funds
0.16%
New
81
Increased
121
Reduced
108
Closed
58
Calls
$65.2M
Puts
$30M
Net Calls
+$35.2M
Net Calls Change
+$29.2M

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
$150M
2
Millennium Management
Millennium Management
New York
$105M
3
PCH
Polar Capital Holdings
United Kingdom
$39.5M
4
Balyasny Asset Management
Balyasny Asset Management
Illinois
$30.4M
5
WP
Woodline Partners
California
$29M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$251M
2
Citadel Advisors
Citadel Advisors
Florida
$59.1M
3
O
OrbiMed
New York
$0
4
Invesco
Invesco
Georgia
$10.1M
5
CCM
Camber Capital Management
Massachusetts
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
WIM
301
Westside Investment Management
California
$9.23K +$9.23K +231 New
TPWA
302
Twin Peaks Wealth Advisors
California
$8.9K +$8.9K +215 New
GTAM
303
Global Trust Asset Management
Florida
$8.61K -$7.15K -181 -45%
HI
304
Harbour Investments
Wisconsin
$7.9K -$27.7K -700 -78%
AUB
305
Atlantic Union Bankshares
Virginia
$7.9K +$7.9K +200 New
AWM
306
AllSquare Wealth Management
New York
$7.82K – – –
NA
307
NewEdge Advisors
Louisiana
$7.74K -$56.3K -1,425 -88%
RAM
308
Riggs Asset Management
Pennsylvania
$7.39K -$2.49K -63 -25%
AAP
309
Arax Advisory Partners
Colorado
$6.17K +$2.06K +52 +50%
PP
310
Pacifica Partners
Canada
$5.97K – – –
WPA
311
Wealth Preservation Advisors
Tennessee
$5.93K – – –
AAS
312
Ameritas Advisory Services
Nebraska
$5.77K +$5.77K +146 New
GWM
313
Geneos Wealth Management
Colorado
$5.49K +$5.49K +139 New
GSWM
314
Golden State Wealth Management
California
$4.98K – – –
SWM
315
Spire Wealth Management
Virginia
$4.94K – – –
GWSG
316
GPS Wealth Strategies Group
Colorado
$4.7K – – –
BWL
317
Bogart Wealth LLC
Virginia
$4.66K +$632 +16 +16%
MAS
318
MPWM Advisory Solutions
Georgia
$4.35K – – –
KIM
319
Kestra Investment Management
Texas
$4.13K – – –
MPWT
320
MassMutual Private Wealth & Trust
Connecticut
$4.07K -$6.28K -159 -61%
CAM
321
Creekmur Asset Management
Illinois
$3.95K – – –
MAM
322
Meeder Asset Management
Ohio
$3.91K +$158 +4 +4%
SFA
323
Semmax Financial Advisors
North Carolina
$3.29K – – –
OCM
324
Orion Capital Management
California
$3.16K – – –
AssetMark Inc
325
AssetMark Inc
California
$2.96K +$2.37K +60 +400%
11 12
13
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