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First Trust NYSE Arca Biotechnology Index Fund

250 hedge funds and large institutions have $510M invested in First Trust NYSE Arca Biotechnology Index Fund in 2025 Q2 according to their latest regulatory filings, with 14 funds opening new positions, 62 increasing their positions, 101 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

1.7% less ownership

Funds ownership: 52.29%50.59% (-1.7%)

7% less funds holding

Funds holding: 269250 (-19)

12% less capital invested

Capital invested by funds: $578M → $510M (-$67.7M)

39% less repeat investments, than reductions

Existing positions increased: 62 | Existing positions reduced: 101

53% less first-time investments, than exits

New positions opened: 14 | Existing positions closed: 30

Holders
250
Holders Change
-19
Holders Change %
-7.06%
% of All Funds
3.29%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
14
Increased
62
Reduced
101
Closed
30
Calls
$2.82M
Puts
Net Calls
+$2.82M
Net Calls Change
+$475K
Name Holding Trade Value Shares
Change
Change in
Stake
PS
176
Principal Securities
Iowa
$135K +$17.4K +109 +15%
Qube Research & Technologies (QRT)
177
Qube Research & Technologies (QRT)
United Kingdom
$114K -$367K -2,301 -76%
HIA
178
Harbor Investment Advisory
Maryland
$99.2K
Bessemer Group
179
Bessemer Group
New Jersey
$97K -$15.9K -100 -14%
GI
180
GAMMA Investing
California
$91.3K
GWM
181
Geneos Wealth Management
Colorado
$88.1K -$54.5K -342 -39%
RWM
182
RMG Wealth Management
Wisconsin
$79.6K +$77.4K +486 New
DWS
183
Dynamic Wealth Strategies
California
$75K
TFGT
184
TS Financial Group (TSFG)
Illinois
$71K
CFD
185
Creative Financial Designs
Indiana
$57.5K +$4.3K +27 +8%
William Blair & Company
186
William Blair & Company
Illinois
$52.4K
DFA
187
DHJJ Financial Advisors
Illinois
$46.6K
TAM
188
Tucker Asset Management
Colorado
$46.6K +$33.9K +213 +280%
PSFG
189
Park Square Financial Group
Georgia
$39.4K -$62.8K -394 -62%
CMA
190
Cedar Mountain Advisors
Oregon
$39.3K
WB
191
Webster Bank
Connecticut
$38.4K
CA
192
CoreCap Advisors
Michigan
$36.8K
EAM
193
Eukles Asset Management
Ohio
$34.2K
IBOK
194
Independence Bank of Kentucky
Kentucky
$32.3K
NC
195
North Capital
Utah
$32.3K
S
196
SignatureFD
Georgia
$29K
WWMSC
197
Wagner Wealth Management (South Carolina)
South Carolina
$28.6K -$796 -5 -3%
CFFP
198
Center for Financial Planning
Michigan
$28.2K
AG
199
AmeriFlex Group
Nevada
$26.5K -$17.5K -110 -40%
CI
200
CX Institutional
Indiana
$24K

FBT Hedge Fund Activity: Q2 2025 in Review

250 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in First Trust NYSE Arca Biotechnology Index Fund (FBT) for Q2 2025, worth a combined $510M — down 12% from $578M a quarter earlier.

Sellers outnumbered buyers: 30 funds closed out of FBT and 14 opened new positions — a net loss of 16 holders — while 101 trimmed existing stakes and 62 added.

The largest buyer was Susquehanna International Group, adding an estimated $7.28M. The largest seller was Stonebridge Financial Group (Pennsylvania), exiting entirely with an estimated $13.1M sold.

  • 250 institutional investors held First Trust NYSE Arca Biotechnology Index Fund (FBT) as of Q2 2025, down from 269 in Q1 2025.
  • Funds reported $510M of First Trust NYSE Arca Biotechnology Index Fund stock for Q2 2025, down 12% quarter-over-quarter.
  • 14 funds opened new First Trust NYSE Arca Biotechnology Index Fund positions in Q2 2025 and 30 closed out, a net change of -16 holders.
  • The largest First Trust NYSE Arca Biotechnology Index Fund buyer in Q2 2025 was Susquehanna International Group, an estimated $7.28M added.
  • The largest First Trust NYSE Arca Biotechnology Index Fund seller in Q2 2025 was Stonebridge Financial Group (Pennsylvania), an estimated $13.1M sold.

Based on aggregated 13F filings for Q2 2025.