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Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$2.17B +$709M +1,830,651 +50%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$1.29B -$210M -542,350 -14%
Artisan Partners
3
Artisan Partners
Wisconsin
$1.26B +$5.86M +15,123 +0.5%
Janus Henderson Group
4
Janus Henderson Group
$873M +$170M +439,889 +25%
T. Rowe Price Investment Management
5
T. Rowe Price Investment Management
Maryland
$833M +$362M +933,365 +79%
Capital World Investors
6
Capital World Investors
California
$734M -$37.4M -96,606 -5%
ACA
7
Avoro Capital Advisors
New York
$488M +$1.51M +3,900 +0.3%
BlackRock
8
BlackRock
New York
$412M +$21.4M +55,252 +6%
BG
9
Bellevue Group
Switzerland
$319M -$22.5M -58,192 -7%
Morgan Stanley
10
Morgan Stanley
New York
$273M +$15.9M +40,993 +6%
RI
11
RTW Investments
New York
$263M
ClearBridge Investments
12
ClearBridge Investments
New York
$235M +$61.8M +159,480 +37%
PBA
13
Paradigm Biocapital Advisors
New York
$217M +$50.2M +129,543 +31%
Holocene Advisors
14
Holocene Advisors
New York
$192M -$15.5M -39,898 -8%
Massachusetts Financial Services
15
Massachusetts Financial Services
Massachusetts
$168M -$64.4M -166,119 -28%
Invesco
16
Invesco
Georgia
$165M -$6.62M -17,078 -4%
SEI Investments
17
SEI Investments
Pennsylvania
$130M -$368K -950 -0.3%
Pictet Asset Management
18
Pictet Asset Management
Switzerland
$130M +$6.18M +15,947 +5%
DTC
19
Deep Track Capital
Connecticut
$118M
Wellington Management Group
20
Wellington Management Group
Massachusetts
$109M -$1.16M -2,996 -1%
Bank of America
21
Bank of America
North Carolina
$108M +$52.3M +134,905 +97%
Federated Hermes
22
Federated Hermes
Pennsylvania
$106M -$34.1M -88,073 -25%
BAMCO Inc
23
BAMCO Inc
New York
$105M -$8.02M -20,705 -7%
AC
24
Armistice Capital
New York
$104M -$20.9M -54,000 -17%
American Century Companies
25
American Century Companies
Missouri
$101M +$38.8M +100,145 +64%