|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$94.1M
|
+$24.1M
|
+737,139
|
+98%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$60.7M
|
+$28.2M
|
+861,754
|
+862%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$50.8M
|
+$12.3M
|
+375,275
|
+87%
|
|
|
4
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$50.5M
|
+$11.5M
|
+350,000
|
+78%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$50.1M
|
+$13.7M
|
+418,344
|
+112%
|
|
|
6
|
Consonance Capital Management
New York
|
$49.5M
|
+$25.7M
|
+783,869
|
New
|
|
|
7
|
Adage Capital Partners
Boston,
Massachusetts
|
$47.7M
|
+$19.8M
|
+605,000
|
+403%
|
|
|
8
|
VHCP Management II
New York
|
$41M
|
+$86.8K
|
+2,650
|
+0.4%
|
|
|
9
|
Millennium Management
New York
|
$37.6M
|
+$19.5M
|
+595,514
|
New
|
|
|
10
|
Janus Henderson Group
London,
|
$35.7M
|
+$18.5M
|
+565,285
|
New
|
|
|
11
|
Perceptive Advisors
New York
|
$33.9M
|
+$2.86M
|
+87,361
|
+19%
|
|
|
12
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$33.4M
|
+$90.4K
|
+2,760
|
+0.5%
|
|
|
13
|
|
$31.6M
|
–
|
–
|
–
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$28.9M
|
+$3.52M
|
+107,600
|
+31%
|
|
|
15
|
Deerfield Management
New York
|
$23.1M
|
-$4.68M
|
-143,061
|
-28%
|
|
|
16
|
Acuta Capital Partners
Redwood City,
California
|
$20.4M
|
+$3.5M
|
+106,745
|
+49%
|
|
|
17
|
Cormorant Asset Management
Boston,
Massachusetts
|
$18.3M
|
+$9.5M
|
+290,000
|
New
|
|
|
18
|
Jennison Associates
New York
|
$18.1M
|
+$5.3M
|
+161,846
|
+130%
|
|
|
19
|
Ghost Tree Capital
New York
|
$15.8M
|
-$83K
|
-2,534
|
-1%
|
|
|
20
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$13.3M
|
+$6.9M
|
+210,716
|
New
|
|
|
21
|
|
$12.6M
|
+$4.77M
|
+145,663
|
+268%
|
|
|
22
|
Redmile Group
San Francisco,
California
|
$12.6M
|
+$6.55M
|
+200,000
|
New
|
|
|
23
|
|
$11.3M
|
-$669K
|
-20,440
|
-10%
|
|
|
24
|
|
$11.1M
|
+$823K
|
+25,129
|
+17%
|
|
|
25
|
Renaissance Technologies
New York
|
$10.5M
|
+$5.46M
|
+166,827
|
New
|
|
