|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$16M
|
+$15.7M
|
+753,892
|
New
|
|
|
2
|
VHCP Management II
New York
|
$13.6M
|
+$13.5M
|
+647,015
|
New
|
|
|
3
|
Deerfield Management
New York
|
$10.8M
|
+$10.6M
|
+509,022
|
New
|
|
|
4
|
|
$10.6M
|
+$10.4M
|
+500,000
|
New
|
|
|
5
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$9.54M
|
+$9.37M
|
+450,000
|
New
|
|
|
6
|
Perceptive Advisors
New York
|
$9.54M
|
+$9.37M
|
+450,000
|
New
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$8.12M
|
+$7.97M
|
+382,790
|
New
|
|
|
8
|
Franklin Resources
San Mateo,
California
|
$7.42M
|
+$7.29M
|
+350,000
|
New
|
|
|
9
|
Avoro Capital Advisors
New York
|
$4.57M
|
+$4.49M
|
+215,597
|
New
|
|
|
10
|
Ghost Tree Capital
New York
|
$4.16M
|
+$4.09M
|
+196,287
|
New
|
|
|
11
|
|
$3.88M
|
+$4.16M
|
+200,000
|
New
|
|
|
12
|
Foresite Capital Management III
Larkspur,
California
|
$3.74M
|
+$3.67M
|
+176,500
|
New
|
|
|
13
|
Acuta Capital Partners
Redwood City,
California
|
$3.24M
|
+$3.18M
|
+152,837
|
New
|
|
|
14
|
|
$3.19M
|
+$3.13M
|
+150,401
|
New
|
|
|
15
|
Adage Capital Partners
Boston,
Massachusetts
|
$3.18M
|
+$3.12M
|
+150,000
|
New
|
|
|
16
|
Fidelity International
Hamilton,
Bermuda
|
$3.18M
|
+$3.12M
|
+150,000
|
New
|
|
|
17
|
Jennison Associates
New York
|
$2.66M
|
+$2.61M
|
+125,285
|
New
|
|
|
18
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.53M
|
+$2.48M
|
+119,146
|
New
|
|
|
19
|
AWM Investment Company
New York
|
$2.12M
|
+$2.08M
|
+100,000
|
New
|
|
|
20
|
Baker Bros. Advisors
New York
|
$2.12M
|
+$2.08M
|
+100,000
|
New
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.59M
|
+$1.56M
|
+75,000
|
New
|
|
|
22
|
Monashee Investment Management
Boston,
Massachusetts
|
$1.38M
|
+$1.35M
|
+65,000
|
New
|
|
|
23
|
DAFNA Capital Management
Los Angeles,
California
|
$848K
|
+$833K
|
+40,000
|
New
|
|
|
24
|
|
$530K
|
+$520K
|
+24,970
|
New
|
|
|
25
|
Weiss Multi-Strategy Advisers
New York
|
$371K
|
+$364K
|
+17,500
|
New
|
|
