Squarepoint
XBI icon

Squarepoint’s State Street SPDR S&P Biotech ETF XBI Stock Holding History

Squarepoint’s Portfolio XBI Stock Details XBI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$212M Buy
1,662,700
+1,506,600
+965% +$188M 0.25% 55
2025
Q4 		$19M Sell
156,100
-210,100
-57% -$24.1M 0.02% 759
2025
Q3 		$36.7M Buy
366,200
+207,500
+131% +$18.7M 0.04% 509
2025
Q2 		$13.2M Sell
158,700
-165,400
-51% -$13.2M 0.01% 946
2025
Q1 		$26.3M Sell
324,100
-603,600
-65% -$54M 0.03% 568
2024
Q4 		$83.5M Buy
927,700
+709,900
+326% +$68.8M 0.08% 236
2024
Q3 		$21.5M Sell
217,800
-268,900
-55% -$26.4M 0.03% 561
2024
Q2 		$45.1M Buy
486,700
+41,200
+9% +$3.69M 0.07% 277
2024
Q1 		$42.3M Buy
445,500
+111,500
+33% +$10.3M 0.07% 311
2023
Q4 		$29.8M Buy
334,000
+123,800
+59% +$9.19M 0.06% 394
2023
Q3 		$15.3M Buy
+210,200
New +$16.8M 0.04% 575
2022
Q4 		– Sell
-28,300
Closed -$2.25M – 3652
2022
Q3 		$2.25M Hold
28,300
– – 0.01% 1253
2022
Q2 		$2.1M Sell
28,300
-33,200
-54% -$2.49M 0.01% 1150
2022
Q1 		$5.53M Buy
61,500
+21,300
+53% +$1.97M 0.02% 682
2021
Q4 		$4.5M Buy
40,200
+11,900
+42% +$1.44M 0.01% 840
2021
Q3 		$3.56M Hold
28,300
– – 0.01% 933
2021
Q2 		$3.83M Buy
+28,300
New +$3.72M 0.01% 855

Other funds holding XBI

BNP Paribas Financial Markets
BNP Paribas Financial Markets Paris, France $206B AUM 31.61% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
Citigroup
Citigroup New York $235B AUM 32.99% 1-Year Est. Return
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund Toronto, Ontario, Canada $62.2B AUM 31.35% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Barclays
Barclays London, United Kingdom $416B AUM 33.63% 1-Year Est. Return
Wells Fargo
Wells Fargo San Francisco, California $530B AUM 22.01% 1-Year Est. Return

Squarepoint's XBI Position: Q4 2025 in Review

Squarepoint sold out of State Street SPDR S&P Biotech ETF (XBI) in Q4 2025, closing a stake of 97,917 shares — an estimated $11.2M sold.

Squarepoint first reported a position in XBI in Q4 2019 and held it in 14 quarters. The position peaked at $77.5M in Q1 2025. 813 funds tracked by Wall St. Rank hold XBI as of Q4 2025.

  • Squarepoint reported no remaining State Street SPDR S&P Biotech ETF position as of Q4 2025 after selling out during the quarter.
  • Squarepoint sold 97,917 State Street SPDR S&P Biotech ETF shares in Q4 2025, an estimated $11.2M.
  • Squarepoint first reported a position in State Street SPDR S&P Biotech ETF in Q4 2019 and held it in 14 quarters.
  • Squarepoint's State Street SPDR S&P Biotech ETF position peaked at $77.5M in Q1 2025.
  • 813 funds tracked by Wall St. Rank held State Street SPDR S&P Biotech ETF as of Q4 2025.

Based on Squarepoint's 13F filing for Q4 2025, filed 13 Feb 2026.