Squarepoint
XBI icon

Squarepoint’s State Street SPDR S&P Biotech ETF XBI Stock Holding History

Squarepoint’s Portfolio XBI Stock Details XBI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$54.9M Buy
430,000
+108,700
+34% +$13.6M 0.06% 310
2025
Q4 		$39.2M Buy
321,300
+212,100
+194% +$24.3M 0.04% 493
2025
Q3 		$10.9M Sell
109,200
-18,700
-15% -$1.68M 0.01% 1030
2025
Q2 		$10.6M Sell
127,900
-120,000
-48% -$9.57M 0.01% 1043
2025
Q1 		$20.1M Sell
247,900
-492,400
-67% -$44M 0.02% 683
2024
Q4 		$66.7M Buy
740,300
+392,500
+113% +$38M 0.07% 290
2024
Q3 		$34.4M Sell
347,800
-154,800
-31% -$15.2M 0.05% 367
2024
Q2 		$46.6M Sell
502,600
-34,100
-6% -$3.06M 0.08% 261
2024
Q1 		$50.9M Buy
536,700
+252,900
+89% +$23.5M 0.09% 252
2023
Q4 		$25.3M Buy
283,800
+233,200
+461% +$17.3M 0.05% 458
2023
Q3 		$3.69M Hold
50,600
– – 0.01% 1376
2023
Q2 		$4.21M Buy
+50,600
New +$4.23M 0.01% 1171
2022
Q2 		– Sell
-28,900
Closed -$2.6M – 3451
2022
Q1 		$2.6M Buy
+28,900
New +$2.67M 0.01% 997

Other funds holding XBI

BNP Paribas Financial Markets
BNP Paribas Financial Markets Paris, France $206B AUM 31.61% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.37T AUM 24.88% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
Citigroup
Citigroup New York $235B AUM 32.99% 1-Year Est. Return
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund Toronto, Ontario, Canada $62.2B AUM 31.35% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Barclays
Barclays London, United Kingdom $416B AUM 33.63% 1-Year Est. Return
Wells Fargo
Wells Fargo San Francisco, California $530B AUM 22.01% 1-Year Est. Return

Squarepoint's XBI Position: Q4 2025 in Review

Squarepoint sold out of State Street SPDR S&P Biotech ETF (XBI) in Q4 2025, closing a stake of 97,917 shares — an estimated $11.2M sold.

Squarepoint first reported a position in XBI in Q4 2019 and held it in 14 quarters. The position peaked at $77.5M in Q1 2025. 813 funds tracked by Wall St. Rank hold XBI as of Q4 2025.

  • Squarepoint reported no remaining State Street SPDR S&P Biotech ETF position as of Q4 2025 after selling out during the quarter.
  • Squarepoint sold 97,917 State Street SPDR S&P Biotech ETF shares in Q4 2025, an estimated $11.2M.
  • Squarepoint first reported a position in State Street SPDR S&P Biotech ETF in Q4 2019 and held it in 14 quarters.
  • Squarepoint's State Street SPDR S&P Biotech ETF position peaked at $77.5M in Q1 2025.
  • 813 funds tracked by Wall St. Rank held State Street SPDR S&P Biotech ETF as of Q4 2025.

Based on Squarepoint's 13F filing for Q4 2025, filed 13 Feb 2026.